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Compare Vertex Pharmaceuticals Incorporated (VRTX) vs Zeta Global Holdings Corp (ZETA) Price & Performance

Vertex Pharmaceuticals IncorporatedTrade
Zeta Global Holdings CorpTrade

Price performance (Past 24H)

Key statistics

Vertex Pharmaceuticals Incorporated vs Zeta Global Holdings Corp — how do they compare? Vertex Pharmaceuticals Incorporated trades at $529.5 (market cap $134.25B), while Zeta Global Holdings Corp trades at $28.51 (market cap $7.32B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 18.3× Zeta Global Holdings Corp's market cap. Which is the better fit depends on your goals.

VRTXZETA
Market Cap
$134.25B$7.32B
Sector
HealthTechnology
52-Week High
$529.65$29.15
52-Week Low
$376.62$14.55
Enterprise Value
$128.37B$7.20B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals (VRTX) trades at $525.72, up 0.35% on the day, with a bullish technical outlook supported by moving averages and strong institutional sentiment. The company reported Q2 2026 revenue of $3.3 billion, beating estimates, and raised its full-year sales guidance, driven by cystic fibrosis drug strength and new product contributions. Profitability remains robust with a 35% net income margin, though the P/E ratio of 30.85 reflects premium valuation.

Outlook is positive with 84% analyst buy ratings and a $534.25 consensus target, but risks include earnings volatility and competitive pressures. Upside hinges on execution of new launches and sustained CF franchise growth, while any clinical or regulatory setbacks could pressure the stock.

Zeta Global Holdings Corp

ZETA stock trades at $28.62, up 3.92% in the past 24 hours, with a bullish technical signal from moving averages and strong support at $28. The company reported its 20th consecutive beat-and-raise quarter in Q2 2026, with revenue up 44% year-over-year and achieving its first GAAP net income. Analyst consensus is strongly bullish with a $30.44 price target, and recent news highlights AI-driven growth and a partnership with Palantir.

The outlook for ZETA is positive due to robust revenue growth, expanding AI adoption, and improving profitability, but risks include a rich valuation with a P/S of 4.35 and EV/EBITDA of 95.89, execution challenges in integrating acquisitions, and competitive pressures in the marketing tech sector. The stock's proximity to its 52-week high suggests limited near-term upside without continued strong earnings performance.

Returns comparison

Trailing returns across standard periods

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Read more on VRTX

About Zeta Global Holdings Corp

Zeta Global is a leading data-driven marketing technology company that provides an omnichannel AI Marketing Cloud. By leveraging a proprietary data cloud of over 2.4 billion deterministic identities, it enables enterprise brands to acquire, grow, and retain customers through predictive intelligence and automated, agentic workflows.

Read more on ZETA