Compare Vertex Pharmaceuticals Incorporated (VRTX) vs State Street PDR S&P Retail ETF (XRT) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Vertex Pharmaceuticals Incorporated vs State Street PDR S&P Retail ETF — how do they compare? Vertex Pharmaceuticals Incorporated trades at $522.29 (market cap $134.06B), while State Street PDR S&P Retail ETF trades at $84.3. The key difference: Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, State Street PDR S&P Retail ETF nearer its low. Which is the better fit depends on your goals.
| VRTX | XRT | |
|---|---|---|
Market Cap | $134.06B | — |
Sector | Health | Broad Market / Factor |
52-Week High | $557.96 | $92.35 |
52-Week Low | $376.62 | $77.28 |
Enterprise Value | $128.18B | — |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Vertex Pharmaceuticals (VRTX) trades at $528.9, down 3.15% on the day, amid a mixed technical and fundamental backdrop. The stock shows a bullish moving average signal but neutral oscillators, with key support at $522. Fundamentally, 2025 revenue reached $12.0B with a strong net income margin of 35%, though recent quarterly EPS results have been mixed. The company recently completed the acquisition of Crinetics Pharmaceuticals, signaling growth ambitions.
The outlook remains positive given analyst consensus favoring a Buy rating (84%) and a $548.78 price target, implying upside. Key opportunities include revenue growth from new drug launches, while risks involve competitive pressures and earnings volatility. The stock's current valuation at a P/E of 30.8 requires sustained execution to justify further gains.
XRT (SPDR S&P Retail ETF) trades at $85.70, down 2.16% amid bearish technical signals, with moving averages indicating a downtrend and RSI levels in neutral territory. Recent news highlights unusual options activity with a 145% surge in put volume (Defense World, 2026-09-09) and mixed retail sector data, including a 0.6% drop in July sales (ETF Trends, 2026-08-14). The ETF offers exposure to consumer discretionary retail, with a dividend scheduled for June 2026.
Outlook is cautious due to technical weakness and sector headwinds like inflation and shifting consumer spending. Risks include economic sensitivity and competitive pressures, but potential exists if retail resilience improves. Investors should weigh bearish signals against long-term value opportunities in selective retail segments.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →About State Street PDR S&P Retail ETF
XRT is an equal-weighted ETF that tracks the U.S. retail sector. It provides diversified exposure to apparel, automotive, and online retailers, including well-known names like Amazon, Target, and Costco.
Read more on XRT →
