Compare Vanguard S&P 500 ETF (VOO) vs State Street SPDR S&P Biotech ETF (XBI) Price & Performance

Vanguard S&P 500 ETFTrade

State Street SPDR S&P Biotech ETFTrade

Price performance (Past 24H)

Key statistics

Vanguard S&P 500 ETF vs State Street SPDR S&P Biotech ETF — how do they compare? Vanguard S&P 500 ETF trades at $687.4, while State Street SPDR S&P Biotech ETF trades at $154.49. Which is the better fit depends on your goals.

	VOO	XBI
Sector	Broad Market / Factor	Broad Market / Factor
52-Week High	$698.29	$164.28
52-Week Low	$571.45	$85.16

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Returns comparison

Trailing returns across standard periods

Top news

Latest headlines on both assets

VOO

Buy rating maintained on US index assets despite AI sector volatility and bubble concerns.Seeking Alpha · 4 hours agoBullish DIA ETF underperforms S&P 500 ETFs due to higher fees and price-weighted index design.24/7 Wall Street · 3 days agoBearish SPY ETF charges higher fees than its cheaper sibling SPYM with identical S&P 500 exposure.24/7 Wall Street · 4 days agoBearish View details →

XBI

Healthcare ETFs lead State Street's top 5 performers with pharma fund gaining 11.7% in the past monthETF Trends · 4 days agoBullish View details →

About Vanguard S&P 500 ETF

VOO is a foundational ETF that tracks the S&P 500 Index, providing exposure to 500 of the largest and most established companies in the United States. Renowned for its ultra-low expense ratio and tax efficiency, it serves as a core building block for long-term investors seeking to capture the total return of the U.S. large-cap market in a single, highly liquid vehicle.

About State Street SPDR S&P Biotech ETF

XBI is an equal-weighted ETF that tracks the U.S. biotechnology segment. It provides diversified exposure to small, mid, and large-cap biotech firms involved in drug discovery and medical research, such as Moderna and Exact Sciences.