Investment
Features
FeesSafety
Academy
More
Pluang+

Compare Vanguard S&P 500 ETF (VOO) vs Vertex Pharmaceuticals Incorporated (VRTX) Price & Performance

Vanguard S&P 500 ETFTrade
Vertex Pharmaceuticals IncorporatedTrade

Price performance (Past 24H)

Key statistics

Vanguard S&P 500 ETF vs Vertex Pharmaceuticals Incorporated — how do they compare? Vanguard S&P 500 ETF trades at $715.34 (market cap $1.80T), while Vertex Pharmaceuticals Incorporated trades at $510.9 (market cap $127.55B). The key difference: Vanguard S&P 500 ETF is far larger — about 14.1× Vertex Pharmaceuticals Incorporated's market cap, and Vanguard S&P 500 ETF is trading nearer its 52-week high, Vertex Pharmaceuticals Incorporated nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Vanguard S&P 500 ETF for 55 Days and Vertex Pharmaceuticals Incorporated for 120 Days on average.

VOOVRTX
Market Cap
$1.80T$127.55B
Volume
4,722,2711,487,944
Sector
Broad Market / FactorHealth
52-Week High
$716.17$557.96
52-Week Low
$580.93$407.37
Typical Hold Time
55 Days120 Days
Enterprise Value
—$121.68B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Vanguard S&P 500 ETF

VOO trades at $713.62, down slightly by 0.11% with a bullish technical signal from moving averages. The ETF shows neutral momentum oscillators with RSI at 68.50 suggesting mild overbought conditions. Recent news highlights VOO's role in long-term wealth building through capital growth rather than dividends, with one article positioning it as a recession-resistant holding.

VOO offers diversified exposure to S&P 500 companies with strong institutional backing. Key risks include market volatility from interest rate uncertainty and potential earnings growth slowdown from 35% to 15% in 2027. The ETF remains a core holding for long-term investors despite short interest increasing 46.9% in September.

Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals (VRTX) trades at $505.64, up 0.63% with mixed technical signals showing bearish moving averages but neutral oscillators. The company maintains strong fundamentals with $12B revenue, 35% net margin, and robust cash flow. Recent positive Phase 2b data for kidney drug inaxaplin and cystic fibrosis dominance support growth. Earnings show volatility with Q1 beat but Q2 miss against expectations.

Outlook remains positive with 84% analyst buy ratings and $573.50 consensus target offering 13% upside. Key risks include clinical trial outcomes, competitive pressures, and reliance on cystic fibrosis portfolio. The stock presents growth potential through pipeline expansion but faces sector volatility and execution challenges.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

VOO
73% Buy27% Sell
Avg holding period · 55 Days
VRTX
100% Buy0% Sell
Avg holding period · 120 Days

Top news

Latest headlines on both assets

About Vanguard S&P 500 ETF

VOO is a foundational ETF that tracks the S&P 500 Index, providing exposure to 500 of the largest and most established companies in the United States. Renowned for its ultra-low expense ratio and tax efficiency, it serves as a core building block for long-term investors seeking to capture the total return of the U.S. large-cap market in a single, highly liquid vehicle.

Read more on VOO →

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Read more on VRTX →