Compare US Bancorp (USB) vs Vertex Pharmaceuticals Incorporated (VRTX) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
US Bancorp vs Vertex Pharmaceuticals Incorporated — how do they compare? US Bancorp trades at $63.7 (market cap $98.36B), while Vertex Pharmaceuticals Incorporated trades at $478.12 (market cap $121.95B). The key difference: Vertex Pharmaceuticals Incorporated is the larger of the two by market cap, and US Bancorp pays a 3.29% dividend while Vertex Pharmaceuticals Incorporated pays none. Which is the better fit depends on your goals.
| USB | VRTX | |
|---|---|---|
Market Cap | $98.36B | $121.95B |
Sector | Financials | Health |
52-Week High | $64.01 | $529.59 |
52-Week Low | $43.94 | $366.54 |
Dividend Yield | 3.29% | — |
Enterprise Value | — | $116.69B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
U.S. Bancorp (USB) trades at $63.71, up 0.9% today, with a bullish technical signal from moving averages. The stock shows strong fundamentals with three consecutive quarterly EPS beats, a P/E of 12.6, and a net income margin of 27.61%. Recent Q2 2026 results highlighted record revenue driven by loan growth and fee income, with the company raising its full-year revenue outlook to 7%-9% growth. Analyst consensus is a Buy with a $70.17 price target, indicating 10% upside potential.
The outlook for USB is positive, supported by earnings momentum, dividend yield near 3%, and institutional optimism. Key risks include rising debt-to-asset ratios, potential credit quality deterioration, and macroeconomic sensitivity. Investors should weigh the stock's attractive valuation against sector-wide interest rate and regulatory uncertainties for balanced exposure.
Vertex Pharmaceuticals (VRTX) trades at $482.00, down 0.75% on the day, with mixed technical signals showing a bullish overall trend but bearish moving averages. The company maintains strong fundamentals with $12.0B revenue (2025), 35.51% net margin, and recent earnings beats. Vertex's $10B acquisition of Crinetics Pharmaceuticals adds significant growth potential in endocrinology treatments.
The outlook remains positive with 85.7% analyst buy ratings and $538 consensus target offering 11.6% upside. Key risks include integration challenges from the Crinetics acquisition and competitive pressures in biopharmaceutical markets. Strong cash flow generation and profitability support continued growth despite recent volatility.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About US Bancorp
As a diversified financial-services provider, U.S. Bancorp is one of the nation's largest regional banks, with branches in well over 20 states, primarily in the Western and Midwestern United States. The bank offers many services, including retail banking, commercial banking, trust and wealth services, credit cards, mortgages, and other payments capabilities.
Read more on USB →About Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →
