Global X Uranium ETF vs State Street SPDR S&P Biotech ETF — how do they compare? Global X Uranium ETF trades at $40.56, while State Street SPDR S&P Biotech ETF trades at $154.43. The key difference: State Street SPDR S&P Biotech ETF is trading nearer its 52-week high, Global X Uranium ETF nearer its low. Which is the better fit depends on your goals.
| URA | XBI | |
|---|---|---|
Sector | Commodities - Metals/Agriculture | Broad Market / Factor |
52-Week High | $61.81 | $164.28 |
52-Week Low | $36.45 | $85.16 |
Trailing returns across standard periods
Latest headlines on both assets
URA provides broad exposure to the global uranium industry and nuclear energy sector. Unlike pure-play mining funds, it includes companies involved in nuclear component production and infrastructure, with top 2026 holdings such as Cameco, Oklo, and Uranium Energy Corp.
Read more on URA →XBI is an equal-weighted ETF that tracks the U.S. biotechnology segment. It provides diversified exposure to small, mid, and large-cap biotech firms involved in drug discovery and medical research, such as Moderna and Exact Sciences.
Read more on XBI →