Twist Bioscience Corp vs 22nd Century Group Inc — how do they compare? Twist Bioscience Corp trades at $88.31 (market cap $5.45B), while 22nd Century Group Inc trades at $4.25 (market cap $1.49M). The key difference: Twist Bioscience Corp is far larger — about 3657.7× 22nd Century Group Inc's market cap. Which is the better fit depends on your goals.
| TWST | XXII | |
|---|---|---|
Market Cap | $5.45B | $1.49M |
Sector | Health | Technology |
52-Week High | $102.88 | $1.07K |
52-Week Low | $24.16 | $3.90 |
Enterprise Value | $5.37B | -$6.74M |
Signals from Pluang's Aura AI — not financial advice
TWST trades at $95.86, up 2.14% today, with a bullish technical signal and strong institutional interest. Revenue growth is robust, rising from $204M in 2022 to $377M in 2025, though the company remains unprofitable with a net income margin of -19.85%. Recent news highlights AI-driven collaborations and earnings beats, but cash flow trends show persistent operational losses.
The outlook is mixed; analyst consensus is bullish with a $91.63 price target, but profitability challenges and negative cash flows pose significant risks. Investment opportunity lies in continued revenue expansion and AI partnerships, while execution risks and high valuations require caution.
No Aura AI signal available yet.
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Latest headlines on both assets
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →22nd Century Group is a plant biotechnology company that uses genetic engineering and gene editing to control the levels of nicotine in tobacco plants. Its flagship product line, VLN®, is the first and only combustible cigarette authorized by the FDA as a Modified Risk Tobacco Product (MRTP), containing 95% less nicotine than traditional cigarettes to help adult smokers smoke less.
Read more on XXII →