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Compare Twist Bioscience Corp (TWST) vs 22nd Century Group Inc (XXII) Price & Performance

Twist Bioscience CorpTrade
22nd Century Group IncTrade

Price performance (Past 24H)

Key statistics

Twist Bioscience Corp vs 22nd Century Group Inc — how do they compare? Twist Bioscience Corp trades at $159.78 (market cap $10.08B), while 22nd Century Group Inc trades at $0.81 (market cap $621.67K). The key difference: Twist Bioscience Corp is far larger — about 16214.4× 22nd Century Group Inc's market cap, and Twist Bioscience Corp is trading nearer its 52-week high, 22nd Century Group Inc nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Twist Bioscience Corp for 27 Days and 22nd Century Group Inc for 32 Days on average.

TWSTXXII
Market Cap
$10.08B$621.67K
Volume
4,229,03745,625
Sector
HealthConsumer Staples
52-Week High
$205.00$483.00
52-Week Low
$25.45$0.80
Typical Hold Time
27 Days32 Days
Enterprise Value
$10.01B-$3.69M

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Twist Bioscience Corp

Twist Bioscience (TWST) trades at $152.05, down 2.31% today but remains near recent highs following a significant rally driven by AI partnerships and strong sector interest. The company shows improving revenue growth ($377M in 2025) but continues to post substantial losses (-$78M net income). Technical indicators show mixed signals with bullish overall sentiment but bearish moving averages, while analyst consensus remains positive with 73% buy ratings.

TWST presents a high-risk, high-reward opportunity with strong growth potential through AI-driven drug discovery partnerships but faces significant execution risks amid persistent profitability challenges. The stock's valuation appears stretched given current fundamentals, requiring successful commercialization of pipeline assets to justify premium multiples.

22nd Century Group Inc

XXII trades at $0.8116, down 8.96% in the last session, with a bearish technical signal from moving averages. The company shows negative profitability metrics including -76.01% net income margin and -284.5% ROE, though valuation ratios appear low with P/S of 0.08 and P/B of 0.03. Recent news highlights regulatory progress in reduced-nicotine tobacco initiatives in France and Europe.

While analyst consensus is 75% buy with a $1,240 price target suggesting significant upside, fundamental challenges persist with consecutive earnings misses and negative cash flow from operations. The stock faces execution risk in commercializing its reduced-nicotine platform amid ongoing losses.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

TWST
100% Buy0% Sell
Avg holding period · 27 Days
XXII
100% Buy0% Sell
Avg holding period · 32 Days

Top news

Latest headlines on both assets

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST →

About 22nd Century Group Inc

22nd Century Group is a plant biotechnology company that uses genetic engineering and gene editing to control the levels of nicotine in tobacco plants. Its flagship product line, VLN®, is the first and only combustible cigarette authorized by the FDA as a Modified Risk Tobacco Product (MRTP), containing 95% less nicotine than traditional cigarettes to help adult smokers smoke less.

Read more on XXII →