Compare Twist Bioscience Corp (TWST) vs Materials Select Sector SPDR Fund (XLB) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Twist Bioscience Corp vs Materials Select Sector SPDR Fund — how do they compare? Twist Bioscience Corp trades at $125.52 (market cap $8.42B), while Materials Select Sector SPDR Fund trades at $51.45. Which is the better fit depends on your goals.
| TWST | XLB | |
|---|---|---|
Market Cap | $8.42B | — |
Sector | Health | — |
52-Week High | $153.10 | $53.67 |
52-Week Low | $24.16 | $42.23 |
Enterprise Value | $8.35B | — |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Twist Bioscience (TWST) trades at $128.06, up 2.68% today, but remains below the analyst consensus price target of $106.14. The stock shows mixed technical signals with bearish overall momentum but bullish moving averages. Fundamentally, the company continues to report losses with a net income margin of -31.66% despite 23% revenue growth in Q3 2026. Recent news highlights AI-driven optimism and institutional buying interest.
TWST presents a high-risk growth story with strong analyst support (79% buy ratings) but persistent profitability challenges. The stock's valuation appears stretched with P/S of 18.09 and P/B of 18.89. Key catalysts include AI drug discovery partnerships and path to EBITDA breakeven, while risks include cash burn and competitive pressures in biotech.
XLB trades at $51.95, down 0.93% on the day, with technical indicators showing a bullish overall signal driven by moving averages. The ETF offers broad exposure to the materials sector, which is benefiting from infrastructure spending and AI-related demand. Recent news highlights the sector's potential for earnings growth and defensive characteristics in the current market environment.
The materials sector appears well-positioned for continued growth with strong Q2 earnings momentum and AI infrastructure tailwinds. However, investors face risks from cyclical sector exposure and potential geopolitical supply chain disruptions. Current technical strength suggests near-term upside potential, though valuation metrics remain unavailable for detailed fundamental assessment.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
About Twist Bioscience Corp
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →About Materials Select Sector SPDR Fund
In seeking to track the performance of the index, the fund employs a replication strategy. It generally invests substantially all, but at least 95%, of its total assets in the securities comprising the index. The index includes securities of companies from the following industries: chemicals; metals and mining; paper and forest products; containers and packaging; and construction materials. The fund is non-diversified.
Read more on XLB →
