Compare Twist Bioscience Corp (TWST) vs Vanguard S&P 500 Growth Index Fund ETF (VOOG) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Twist Bioscience Corp vs Vanguard S&P 500 Growth Index Fund ETF — how do they compare? Twist Bioscience Corp trades at $123.01 (market cap $7.72B), while Vanguard S&P 500 Growth Index Fund ETF trades at $85.22. Which is the better fit depends on your goals.
| TWST | VOOG | |
|---|---|---|
Market Cap | $7.72B | — |
Sector | Health | Broad Market / Factor |
52-Week High | $124.88 | $85.42 |
52-Week Low | $24.16 | $65.32 |
Enterprise Value | $7.65B | — |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
TWST is trading at $124.88, up 7.96% in the last 24 hours, near its pivot point of $121 with resistance at $129. The stock shows strong technical momentum with bullish moving averages, though RSI levels indicate overbought conditions. Revenue growth is robust, with fiscal 2026 Q3 revenue up 23% year-over-year to $118.4 million, but the company remains unprofitable with a net income margin of -31.66% and negative cash flow from operations. Recent news highlights an upsized $300 million public offering and expansion in AI-driven drug discovery.
The outlook for TWST is mixed; bullish analyst sentiment and AI growth potential are offset by persistent losses and high valuation multiples. Investment opportunity lies in sustained revenue expansion and path to profitability, but risks include cash burn, competitive pressures, and execution challenges in scaling operations. The stock's current price exceeds the consensus target of $106.14, suggesting limited near-term upside based on fundamentals.
VOOG trades at $85.18, down slightly by 0.02% today. Technical indicators show a bullish trend with moving averages supporting upside momentum, though the relative strength index suggests potential overbought conditions near-term. Recent news highlights institutional accumulation, including Apella Capital increasing holdings by 463.2% as of August 2026, and the ETF hitting a new 52-week high, reflecting strong investor interest in large-cap growth exposure.
The outlook remains positive given the ETF's low expense ratio of 0.07% and focus on S&P 500 growth stocks, but risks include high concentration in technology sectors and sensitivity to market volatility. Continued institutional inflows and bullish technical signals support further gains, though overbought levels warrant caution.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
About Twist Bioscience Corp
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →About Vanguard S&P 500 Growth Index Fund ETF
VOOG is an index-based ETF that tracks the S&P 500 Growth Index, composed of the growth-oriented companies within the S&P 500. It selects constituents based on three key metrics—sales growth, the ratio of earnings change to price, and momentum—offering a highly liquid and low-cost way to capture the high-performing 'growth slice' of the broader U.S. large-cap market.
Read more on VOOG →
