Compare Twist Bioscience Corp (TWST) vs Vanguard S&P 500 ETF (VOO) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Twist Bioscience Corp vs Vanguard S&P 500 ETF — how do they compare? Twist Bioscience Corp trades at $124.16 (market cap $7.72B), while Vanguard S&P 500 ETF trades at $710.42. Which is the better fit depends on your goals.
| TWST | VOO | |
|---|---|---|
Market Cap | $7.72B | — |
Sector | Health | Broad Market / Factor |
52-Week High | $124.88 | $710.71 |
52-Week Low | $24.16 | $580.93 |
Enterprise Value | $7.65B | — |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
TWST is trading at $124.88, up 7.96% in the last 24 hours, near its pivot point of $121 with resistance at $129. The stock shows strong technical momentum with bullish moving averages, though RSI levels indicate overbought conditions. Revenue growth is robust, with fiscal 2026 Q3 revenue up 23% year-over-year to $118.4 million, but the company remains unprofitable with a net income margin of -31.66% and negative cash flow from operations. Recent news highlights an upsized $300 million public offering and expansion in AI-driven drug discovery.
The outlook for TWST is mixed; bullish analyst sentiment and AI growth potential are offset by persistent losses and high valuation multiples. Investment opportunity lies in sustained revenue expansion and path to profitability, but risks include cash burn, competitive pressures, and execution challenges in scaling operations. The stock's current price exceeds the consensus target of $106.14, suggesting limited near-term upside based on fundamentals.
VOO, the Vanguard S&P 500 ETF, trades at $710.19, down slightly by 0.06% today, with a bullish technical signal from moving averages but neutral oscillators. The ETF is near its pivot point of $709, with immediate resistance at $711. Recent news highlights the S&P 500 at record highs, with JPMorgan raising its year-end target to 8,000, citing strong earnings and AI-driven growth, while some caution emerges from overbought signals and high valuations.
The outlook remains positive given institutional bullishness and AI tailwinds, but risks include market overvaluation, potential pullbacks from overbought conditions, and sensitivity to inflation data. Long-term investors may benefit from dollar-cost averaging, though short-term volatility warrants caution amid elevated sentiment and technical indicators signaling near-term exhaustion.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Twist Bioscience Corp
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →About Vanguard S&P 500 ETF
VOO is a foundational ETF that tracks the S&P 500 Index, providing exposure to 500 of the largest and most established companies in the United States. Renowned for its ultra-low expense ratio and tax efficiency, it serves as a core building block for long-term investors seeking to capture the total return of the U.S. large-cap market in a single, highly liquid vehicle.
Read more on VOO →
