Compare Twist Bioscience Corp (TWST) vs Upwork Inc (UPWK) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Twist Bioscience Corp vs Upwork Inc — how do they compare? Twist Bioscience Corp trades at $124.46 (market cap $7.72B), while Upwork Inc trades at $8.37 (market cap $1.04B). The key difference: Twist Bioscience Corp is far larger — about 7.4× Upwork Inc's market cap, and Twist Bioscience Corp is trading nearer its 52-week high, Upwork Inc nearer its low. Which is the better fit depends on your goals.
| TWST | UPWK | |
|---|---|---|
Market Cap | $7.72B | $1.04B |
Sector | Health | Industrials |
52-Week High | $124.88 | $22.11 |
52-Week Low | $24.16 | $7.84 |
Enterprise Value | $7.65B | $806.15M |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Twist Bioscience (TWST) trades at $123.76, down 0.9% on the day, with a bullish technical signal from moving averages but bearish oscillators. Revenue growth is strong, with 2025 revenue at $376.57 million, though the company remains unprofitable with a net income margin of -31.66%. Recent news highlights an upsized $300 million public offering and an analyst upgrade, contributing to positive sentiment.
The outlook is mixed: robust revenue growth and high analyst buy ratings (78.57%) support upside potential, but persistent losses, negative cash flow, and high valuation ratios pose significant risks. Investors should weigh the growth trajectory against the path to profitability and cash burn concerns.
UPWK is trading at $8.25, down 16.12% amid weak guidance overshadowing a recent Q2 earnings beat. The stock shows bearish technical signals with key support at $8.00. Fundamentally, revenue grew to $787.78M in 2025 with a net income margin of 12.93%, though earnings have been mixed with three misses in the last four quarters. Recent news highlights concerns over declining active clients and AI-driven market shifts.
The outlook is cautious; while valuation ratios like P/E of 10.71 appear reasonable, near-term risks from competitive pressures and investor lawsuits pose headwinds. Analyst consensus is a Buy with a $9.25 target, suggesting potential upside if execution improves, but sentiment remains fragile post-earnings.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Twist Bioscience Corp
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →About Upwork Inc
Upwork Inc is a United States-based company that operates an online marketplace that enables businesses to find and work with highly-skilled independent professionals. The develops platform for hiring and freelancing purposes. Its products offering include Upwork Basic, Upwork Plus, Upwork Business, Upwork Enterprise, and Upwork Payroll. The business generates revenue from Talent and Clients across the USA, India, the Philippines and the rest of the world. Substantial income is derived from providing services to Clients.
Read more on UPWK →
