Twist Bioscience Corp vs Upwork Inc — how do they compare? Twist Bioscience Corp trades at $159.84 (market cap $10.08B), while Upwork Inc trades at $8.64 (market cap $1.07B). The key difference: Twist Bioscience Corp is far larger — about 9.4× Upwork Inc's market cap, and Twist Bioscience Corp is trading nearer its 52-week high, Upwork Inc nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Twist Bioscience Corp for 27 Days and Upwork Inc for 38 Days on average.
| TWST | UPWK | |
|---|---|---|
Market Cap | $10.08B | $1.07B |
Volume | 4,229,037 | 2,574,130 |
Sector | Health | Industrials |
52-Week High | $205.00 | $22.11 |
52-Week Low | $25.45 | $7.84 |
Typical Hold Time | 27 Days | 38 Days |
Enterprise Value | $10.01B | $833.01M |
Signals from Pluang's Aura AI — not financial advice
TWST trades at $155.65, down 6.78% over 24 hours, with a bearish technical signal and negative cash flows. Revenue growth is strong, reaching $377M in 2025, but the company remains unprofitable with a net income margin of -31.66%. Recent news highlights its role in Eli Lilly's AI-driven drug discovery platform, boosting sentiment despite earnings misses.
The outlook is mixed: analyst consensus is bullish with a $145.20 price target, but high valuation multiples and persistent losses pose risks. Investment opportunity hinges on AI partnerships driving future profitability, while execution risks and cash burn require careful monitoring.
Upwork trades at $8.40, up 0.48% on the day, with a bearish technical signal and neutral oscillators. The company reported Q2 2026 EPS of $0.41, beating expectations, but revenue guidance disappointed, causing a recent sell-off. Financials show strong gross margins of 77.21% and a P/E of 10.99, indicating potential undervaluation. Recent news includes insider selling and a securities fraud investigation, adding to investor caution.
The outlook is mixed: solid profitability and low valuation offer upside, but AI disruption risks and weak guidance pose challenges. Analysts are split with a $9.64 price target, suggesting moderate upside from current levels if execution improves and sentiment recovers.
Trailing returns across standard periods
What Pluang investors did over the last 30 days
Latest headlines on both assets
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →Upwork Inc is a United States-based company that operates an online marketplace that enables businesses to find and work with highly-skilled independent professionals. The develops platform for hiring and freelancing purposes. Its products offering include Upwork Basic, Upwork Plus, Upwork Business, Upwork Enterprise, and Upwork Payroll. The business generates revenue from Talent and Clients across the USA, India, the Philippines and the rest of the world. Substantial income is derived from providing services to Clients.
Read more on UPWK →