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Compare Twilio Inc (TWLO) vs Twist Bioscience Corp (TWST) Price & Performance

Twilio IncTrade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

Twilio Inc vs Twist Bioscience Corp — how do they compare? Twilio Inc trades at $289.13 (market cap $42.35B), while Twist Bioscience Corp trades at $161.88 (market cap $10.08B). The key difference: Twilio Inc is far larger — about 4.2× Twist Bioscience Corp's market cap, and Twilio Inc is trading nearer its 52-week high, Twist Bioscience Corp nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Twilio Inc for 56 Days and Twist Bioscience Corp for 27 Days on average.

TWLOTWST
Market Cap
$42.35B$10.08B
Volume
1,862,6424,229,037
Sector
TechnologyHealth
52-Week High
$301.27$205.00
52-Week Low
$106.23$25.45
Typical Hold Time
56 Days27 Days
Enterprise Value
$40.76B$10.01B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Twilio Inc

Twilio (TWLO) trades at $289.18, up 5.93% in the past 24 hours, with a bullish technical signal and strong earnings beats in recent quarters. The company's revenue growth accelerated to $5.07 billion in 2025, with net income turning positive at $33.83 million, and is projected to reach $1.1 billion in 2026. Recent inclusion in the S&P 500 index and positive analyst sentiment with 76.92% buy ratings highlight investor confidence, though high valuation multiples like a P/E of 38.09 and EV/EBITDA of 81.63 suggest premium pricing.

The outlook for Twilio is positive, driven by robust revenue growth, expanding profitability, and strategic positioning in AI-driven communications. Key risks include elevated valuation metrics that may limit upside, competitive pressures, and potential volatility from market reactions to earnings. Institutional interest remains strong, but investors should weigh growth prospects against current premium valuations.

Twist Bioscience Corp

Twist Bioscience (TWST) trades at $162.43, up 4.36% today, showing strong momentum despite recent earnings misses. The stock maintains a bullish technical signal with RSI at 29.02 indicating potential oversold conditions. Fundamentally, revenue growth continues (2025: $377M, 2026: $432M projected) but profitability remains elusive with negative margins. Recent partnership with Eli Lilly's TuneLab platform highlights strategic positioning in AI-driven drug discovery.

While analyst consensus favors Buy (73%), the stock trades above the $145.20 target, suggesting limited near-term upside. Key risks include persistent cash burn (-$44M net CF in 2025) and high valuation multiples (P/S: 21.5). The AI biotech partnership provides growth catalyst potential, but profitability timeline remains uncertain for investors.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

TWLO
100% Buy0% Sell
Avg holding period · 56 Days
TWST
100% Buy0% Sell
Avg holding period · 27 Days

Top news

Latest headlines on both assets

About Twilio Inc

Twilio Inc. is a cloud-based communication platform-as-a-service company offering communication building blocks that allow for a fully customized customer engagement experience spanning voice, video, chat, and SMS messaging. It does this through various application programming interfaces, or APIs, and prebuilt solution applications aimed at improving customer engagement. The company leverages its Super Network, a global network of carrier relationships, to facilitate high-speed, cost-effective communication.

Read more on TWLO →

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST →