ProShares UltraPro Short QQQ ETF vs Twist Bioscience Corp — how do they compare? ProShares UltraPro Short QQQ ETF trades at $33.05 (market cap $2.23B), while Twist Bioscience Corp trades at $163.14 (market cap $10.08B). The key difference: Twist Bioscience Corp is far larger — about 4.5× ProShares UltraPro Short QQQ ETF's market cap, and Twist Bioscience Corp is trading nearer its 52-week high, ProShares UltraPro Short QQQ ETF nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold ProShares UltraPro Short QQQ ETF for 12 Days and Twist Bioscience Corp for 27 Days on average.
| SQQQ | TWST | |
|---|---|---|
Market Cap | $2.23B | $10.08B |
Volume | 60,436,012 | 4,229,037 |
Sector | Leveraged / Inverse | Health |
52-Week High | $89.43 | $205.00 |
52-Week Low | $31.83 | $25.45 |
Typical Hold Time | 12 Days | 27 Days |
Enterprise Value | — | $10.01B |
Signals from Pluang's Aura AI — not financial advice
SQQQ (ProShares UltraPro Short QQQ) trades at $33.20, up 3.49% today, reflecting bearish market sentiment toward the Nasdaq 100. Technical indicators show a predominantly bearish signal with moving averages heavily weighted toward selling pressure. The ETF is designed to deliver triple the inverse daily performance of the Nasdaq 100, making it a tactical tool for hedging or speculating on tech sector declines.
SQQQ's outlook remains tied to Nasdaq 100 volatility, with potential gains during market downturns but significant decay risk in flat or rising markets. Investors should consider the high-risk, leveraged nature of this instrument and its suitability primarily for short-term hedging strategies rather than long-term holdings.
TWST trades at $155.65, down 6.78% over 24 hours, with a bearish technical signal and negative cash flows. Revenue growth is strong, reaching $377M in 2025, but the company remains unprofitable with a net income margin of -31.66%. Recent news highlights its role in Eli Lilly's AI-driven drug discovery platform, boosting sentiment despite earnings misses.
The outlook is mixed: analyst consensus is bullish with a $145.20 price target, but high valuation multiples and persistent losses pose risks. Investment opportunity hinges on AI partnerships driving future profitability, while execution risks and cash burn require careful monitoring.
Trailing returns across standard periods
What Pluang investors did over the last 30 days
Latest headlines on both assets
SQQQ is a leveraged inverse ETF that seeks daily investment results, before fees and expenses, that correspond to three times the inverse (-3x) of the daily performance of the Nasdaq-100 Index. It is a tactical trading tool designed for sophisticated investors to profit from or hedge against declines in large-cap technology and growth stocks. Due to its daily reset and the effects of compounding, it is intended for short-term use and carries significant risk if held during periods of high market volatility.
Read more on SQQQ →Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →