NEOS S&P 500 High Income ETF vs 22nd Century Group Inc — how do they compare? NEOS S&P 500 High Income ETF trades at $54.2, while 22nd Century Group Inc trades at $4.33 (market cap $1.52M). The key difference: NEOS S&P 500 High Income ETF is trading nearer its 52-week high, 22nd Century Group Inc nearer its low. Which is the better fit depends on your goals.
| SPYI | XXII | |
|---|---|---|
Sector | Income / Options Overlay | Technology |
52-Week High | $54.19 | $801.00 |
52-Week Low | $47.98 | $3.72 |
Market Cap | — | $1.52M |
Enterprise Value | — | -$6.71M |
Signals from Pluang's Aura AI — not financial advice
SPYI (NEOS S&P 500 High Income ETF) trades at $54.20, showing minimal daily movement with a 0.02% gain. The ETF employs an options overlay strategy on the S&P 500 to generate high monthly distributions, with recent dividends of $0.53-$0.54. Technical indicators show a bullish trend with strong moving average support, though RSI levels suggest potential overbought conditions. The fund's primary appeal is its ability to provide substantial income while maintaining S&P 500 exposure.
SPYI offers investors a unique income-generating approach through its options strategy, currently yielding approximately 12%. However, concerns exist about whether distributions represent true income versus return of capital. The fund's performance depends heavily on market volatility for option premium generation, creating both opportunity and risk. Investors should weigh the high yield against potential principal erosion in low-volatility environments.
22nd Century Group (XXII) trades at $4.31, down 0.92% on the day, with a neutral technical signal and bearish moving averages. The company shows deep unprofitability with a gross margin of -52.19% and net margin of -65.76%, though revenue was $7.05M in 2025. Recent corporate actions include a 20:1 reverse stock split in June 2026, and news highlights retail expansion for VLN reduced-nicotine cigarettes in California and New York.
The outlook remains speculative with high execution risk amid persistent losses, but analyst sentiment is bullish with 75% buy ratings. Key risks include negative cash flow from operations, regulatory hurdles for tobacco products, and the need for successful commercialization of VLN to achieve profitability.
Trailing returns across standard periods
Latest headlines on both assets
SPYI is an actively managed ETF designed to generate high monthly income through a data-driven call option strategy on the S&P 500 Index. Unlike traditional covered call funds that often forfeit significant upside, SPYI utilizes a 'call spread' approach—selling near-the-money calls while buying out-of-the-money calls—to capture a portion of equity appreciation in rising markets. It prioritizes tax efficiency by utilizing Section 1256 contracts and tax-loss harvesting to provide investors with high-yield monthly distributions.
Read more on SPYI →22nd Century Group is a plant biotechnology company that uses genetic engineering and gene editing to control the levels of nicotine in tobacco plants. Its flagship product line, VLN®, is the first and only combustible cigarette authorized by the FDA as a Modified Risk Tobacco Product (MRTP), containing 95% less nicotine than traditional cigarettes to help adult smokers smoke less.
Read more on XXII →