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Compare Invesco S&P 500 Low Volatility ETF (SPLV) vs Vertex Pharmaceuticals Incorporated (VRTX) Price & Performance

Invesco S&P 500 Low Volatility ETFTrade
Vertex Pharmaceuticals IncorporatedTrade

Price performance (Past 24H)

Key statistics

Invesco S&P 500 Low Volatility ETF vs Vertex Pharmaceuticals Incorporated — how do they compare? Invesco S&P 500 Low Volatility ETF trades at $72.24 (market cap $6.94B), while Vertex Pharmaceuticals Incorporated trades at $511.57 (market cap $127.55B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 18.4× Invesco S&P 500 Low Volatility ETF's market cap, and Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, Invesco S&P 500 Low Volatility ETF nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Invesco S&P 500 Low Volatility ETF for 123 Days and Vertex Pharmaceuticals Incorporated for 120 Days on average.

SPLVVRTX
Market Cap
$6.94B$127.55B
Volume
1,663,7031,487,944
52-Week High
$77.97$557.96
52-Week Low
$70.30$407.37
Typical Hold Time
123 Days120 Days
Sector
—Health
Enterprise Value
—$121.68B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Invesco S&P 500 Low Volatility ETF

SPLV, the Invesco S&P 500 Low Volatility ETF, trades at $72.17 with a 1.33% daily gain. The ETF faces technical headwinds with a bearish moving average signal while oscillators remain neutral. Recent news highlights SPLV's underperformance versus the S&P 500, returning 5% versus 17%, due to sector overweights in Utilities, Real Estate, and Financials. The ETF maintains a 19.5x P/E ratio with upcoming dividend payments scheduled.

SPLV offers defensive exposure during market volatility but faces growth-adjusted valuation concerns. Key risks include concentrated sector exposure and lagging broad market performance. The neutral technical stance and mixed sentiment suggest cautious positioning for investors seeking low-volatility equity exposure amid geopolitical and economic uncertainty.

Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals (VRTX) trades at $509.98, up 0.86% today, with a bearish technical signal but strong fundamentals. The company reported $12.00B revenue in 2025 with a 35% net income margin and robust cash flow. Recent positive Phase 2b data for inaxaplin in kidney disease and dominant cystic fibrosis market position support growth. Analysts maintain a strong buy consensus with a $573.50 price target, indicating 12% upside potential.

Outlook remains positive driven by pipeline expansion and high profitability, though risks include clinical trial outcomes and market volatility. The stock's valuation at 29.31 P/E is reasonable for its growth profile, but investor sentiment is cautious near-term due to mixed earnings beats and technical weakness.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

SPLV
100% Buy0% Sell
Avg holding period · 123 Days
VRTX
100% Buy0% Sell
Avg holding period · 120 Days

About Invesco S&P 500 Low Volatility ETF

The fund generally will invest at least 90% of its total assets in the securities that comprise the underlying index. Strictly in accordance with its guidelines and mandated procedures, S&P Dow Jones Indices LLC (the "index Provider") compiles, maintains and calculates the underlying index, which is designed to measure the performance of the 100 least volatile constituents of the S&P 500 ® Index over the past 12 months as determined by the index Provider.

Read more on SPLV →

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Read more on VRTX →