Summit Therapeutics Inc vs Upstart Holdings Inc — how do they compare? Summit Therapeutics Inc trades at $14.58 (market cap $10.48B), while Upstart Holdings Inc trades at $29.4 (market cap $2.76B). The key difference: Summit Therapeutics Inc is far larger — about 3.8× Upstart Holdings Inc's market cap. Which is the better fit depends on your goals.
| SMMT | UPST | |
|---|---|---|
Market Cap | $10.48B | $2.76B |
Sector | Health | Financials |
52-Week High | $29.32 | $84.13 |
52-Week Low | $13.05 | $24.22 |
Enterprise Value | $9.90B | — |
Signals from Pluang's Aura AI — not financial advice
No Aura AI signal available yet.
Upstart Holdings (UPST) trades at $29.27, down 0.81% on the day, with a bearish technical signal but improving fundamentals. The company reported a net income of $53.60 million in 2025, marking a significant turnaround from prior losses. Recent news highlights AI-driven lending growth and a $600 million funding deal with Neuberger Berman, though quarterly earnings have been mixed with a recent miss in Q1 2026.
The stock presents a high-risk, high-reward opportunity, supported by analyst consensus targets near $42.00 but challenged by volatile cash flows and rising debt. Key risks include execution on new loan products and macroeconomic sensitivity, while institutional sentiment remains divided with a 45% buy rating. Near-term direction hinges on Q2 2026 results due August 4, 2026.
Trailing returns across standard periods
Summit Therapeutics Inc. is a biopharmaceutical company focused on the development and commercialization of new medicines for the treatment of infectious diseases and other unmet medical needs. The company's lead product candidate is an antibiotic for the treatment of Clostridioides difficile infection (CDI), a serious infection of the colon. Summit Therapeutics is committed to bringing innovative therapies to market to address global health challenges and improve patient outcomes.
Read more on SMMT →Upstart Holdings Inc provides credit services. The company provides a proprietary, cloud-based, artificial intelligence lending platform. The platform aggregates consumer demand for loans and connects it to the network of Upstart AI-enabled bank partners. The revenue of the company is primarily comprised of fees paid by banks.
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