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Compare Super Micro Computer Inc (SMCI) vs Twist Bioscience Corp (TWST) Price & Performance

Super Micro Computer IncTrade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

Super Micro Computer Inc vs Twist Bioscience Corp — how do they compare? Super Micro Computer Inc trades at $38.43 (market cap $25.58B), while Twist Bioscience Corp trades at $125.52 (market cap $8.26B). The key difference: Super Micro Computer Inc is far larger — about 3.1× Twist Bioscience Corp's market cap, and Twist Bioscience Corp is trading nearer its 52-week high, Super Micro Computer Inc nearer its low. Which is the better fit depends on your goals.

SMCITWST
Market Cap
$25.58B$8.26B
Sector
TechnologyHealth
52-Week High
$58.68$153.10
52-Week Low
$20.53$24.16
Enterprise Value
$31.04B$8.18B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Super Micro Computer Inc

Super Micro Computer (SMCI) trades at $40.26, up 1.69% with a bullish technical signal and strong AI-driven growth. The stock shows robust fundamentals with revenue reaching $21.97B in 2025 and net income of $1.05B, while consistently beating earnings estimates. Recent news highlights strong AI infrastructure demand and margin improvements, though some caution exists around sustainability.

SMCI presents a compelling growth story fueled by AI server demand, with attractive valuations (P/E 11.94, P/S 0.69) and analyst consensus price target of $40.57. Key risks include margin sustainability concerns and cash flow volatility, but the company's market position and earnings momentum support continued upside potential for investors.

Twist Bioscience Corp

Twist Bioscience (TWST) trades at $128.06, up 2.68% with a bearish technical signal despite recent AI-driven momentum. The company shows strong revenue growth (2025: $377M, 2026: $432M projected) but continues to report significant losses with negative net margins. Recent news highlights AI partnerships and a $300M stock offering, while analyst consensus remains predominantly bullish with 78.6% buy ratings.

TWST presents a high-risk growth opportunity with accelerating revenue but persistent profitability challenges. The stock's valuation appears stretched at P/S of 18.09, requiring successful execution on AI initiatives and path to EBITDA breakeven. Key risks include cash burn, competitive pressures, and dependence on emerging AI-driven drug discovery markets.

Returns comparison

Trailing returns across standard periods

Top news

Latest headlines on both assets

About Super Micro Computer Inc

Super Micro Computer, Inc., commonly known as Supermicro, is a leading provider of high-performance and high-efficiency server technology and innovation. The company specializes in designing, manufacturing, and selling advanced server, storage, and networking solutions, primarily for data centers, cloud computing, artificial intelligence, and 5G/Edge computing markets. SMCI's modular architecture allows for the rapid delivery of customized and purpose-built solutions, making it a key player in the enterprise computing and specialized AI infrastructure space.

Read more on SMCI

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST