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Compare Shopify Inc. (SHOP) vs Twist Bioscience Corp (TWST) Price & Performance

Shopify Inc.Trade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

Shopify Inc. vs Twist Bioscience Corp — how do they compare? Shopify Inc. trades at $165.78 (market cap $211.73B), while Twist Bioscience Corp trades at $154.5 (market cap $10.08B). The key difference: Shopify Inc. is far larger — about 21× Twist Bioscience Corp's market cap, and Shopify Inc. is trading nearer its 52-week high, Twist Bioscience Corp nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Shopify Inc. for 78 Days and Twist Bioscience Corp for 27 Days on average.

SHOPTWST
Market Cap
$211.73B$10.08B
Volume
7,146,6514,229,037
Sector
TechnologyHealth
52-Week High
$179.01$205.00
52-Week Low
$95.40$25.45
Typical Hold Time
78 Days27 Days
Enterprise Value
$206.96B$10.01B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Shopify Inc.

Shopify (SHOP) trades at $165.94, up 0.88% today, showing strong momentum near analyst consensus targets. The stock maintains a bullish technical outlook with solid fundamental growth - revenue increased from $5.6B in 2022 to $11.6B in 2025 while achieving profitability. Recent earnings show mixed results with Q4 2025 missing estimates but Q1 and Q2 2026 beating expectations. The company continues to innovate with AI-powered commerce tools and expanding merchant solutions.

Shopify presents growth potential through e-commerce leadership and AI integration, though elevated valuation metrics (P/E 112, P/S 16) warrant caution. Key risks include competitive pressures from Amazon and valuation sensitivity to growth sustainability. Analyst consensus remains bullish with 67% buy ratings and $168.63 price target, suggesting modest upside from current levels.

Twist Bioscience Corp

TWST trades at $155.65, down 6.78% today, reflecting a bearish technical signal and recent earnings misses. Revenue growth is strong, rising to $376.57M in 2025, but profitability remains elusive with a net income margin of -31.66%. The company's partnership with Lilly TuneLab for AI-driven drug discovery has generated positive news flow, yet cash flow remains negative, and the stock trades at elevated valuation multiples like P/S of 22.01.

The outlook is mixed: strong analyst buy-side consensus (73% Buy) and strategic AI partnerships offer growth potential, but persistent losses, high cash burn, and bearish technicals pose significant risks. Investors face a trade-off between long-term innovation prospects and near-term financial instability.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

SHOP
23% Buy77% Sell
Avg holding period · 78 Days
TWST
37% Buy63% Sell
Avg holding period · 27 Days

Top news

Latest headlines on both assets

About Shopify Inc.

Shopify Inc. provides a cloud-based commerce platform. The Company offers a platform for merchants to create an omni-channel experience that helps showcase the merchant's brand.

Read more on SHOP →

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST →