Sea Limited vs Vertex Pharmaceuticals Incorporated — how do they compare? Sea Limited trades at $107.87 (market cap $69.41B), while Vertex Pharmaceuticals Incorporated trades at $522.29 (market cap $134.06B). The key difference: Vertex Pharmaceuticals Incorporated is the larger of the two by market cap, and Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, Sea Limited nearer its low. Which is the better fit depends on your goals.
| SE | VRTX | |
|---|---|---|
Market Cap | $69.41B | $134.06B |
Sector | Media | Health |
52-Week High | $196.50 | $557.96 |
52-Week Low | $78.16 | $376.62 |
Enterprise Value | $64.44B | $128.18B |
Signals from Pluang's Aura AI — not financial advice
Sea Limited (SE) trades at $113.33, up 1.11% with bullish technical signals and strong analyst support. The company shows robust revenue growth from $16.8B in 2024 to $22.9B in 2025, with net income reaching $1.58B. Recent earnings beat expectations in Q1 and Q2 2026, while operating cash flow improved significantly to $5.02B in 2025. Technical indicators show bullish moving averages with support at $111 and resistance at $115.
SE presents a compelling growth story with expanding profitability and positive cash flow generation. However, elevated valuation multiples (P/E 43.76) and insider selling activity warrant caution. The consensus price target of $143.67 suggests 27% upside potential, but investors should monitor competitive pressures in Southeast Asian markets and execution risks as the company scales.
Vertex Pharmaceuticals (VRTX) trades at $528.9, down 3.15% on the day, amid a mixed technical and fundamental backdrop. The stock shows a bullish moving average signal but neutral oscillators, with key support at $522. Fundamentally, 2025 revenue reached $12.0B with a strong net income margin of 35%, though recent quarterly EPS results have been mixed. The company recently completed the acquisition of Crinetics Pharmaceuticals, signaling growth ambitions.
The outlook remains positive given analyst consensus favoring a Buy rating (84%) and a $548.78 price target, implying upside. Key opportunities include revenue growth from new drug launches, while risks involve competitive pressures and earnings volatility. The stock's current valuation at a P/E of 30.8 requires sustained execution to justify further gains.
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Latest headlines on both assets
Sea Limited offers information technology services. The Company provides online personal computer and mobile digital content, e-commerce, and payment platforms. Sea serves customers worldwide.
Read more on SE →Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →