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Compare Ryanair Holdings plc (RYAAY) vs Twist Bioscience Corp (TWST) Price & Performance

Ryanair Holdings plcTrade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

Ryanair Holdings plc vs Twist Bioscience Corp — how do they compare? Ryanair Holdings plc trades at $54.25 (market cap $27.24B), while Twist Bioscience Corp trades at $125.52 (market cap $8.26B). The key difference: Ryanair Holdings plc is far larger — about 3.3× Twist Bioscience Corp's market cap, and Ryanair Holdings plc pays a 1.66% dividend while Twist Bioscience Corp pays none. Which is the better fit depends on your goals.

RYAAYTWST
Market Cap
$27.24B$8.26B
Sector
IndustrialsHealth
52-Week High
$73.82$153.10
52-Week Low
$53.24$24.16
Enterprise Value
$24.19B$8.18B
Dividend Yield
1.66%

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ryanair Holdings plc

RYAAY trades at $54.37, down 1.79% today, with bearish technical signals but strong fundamentals including 12.13% net margins and 22.41% ROE. Recent earnings show mixed results with a Q1 beat but Q2 miss, while Q3 expectations are high at $3.38 EPS. The company maintains robust cash flow from operations at $3.42B despite net cash flow turning negative in 2025. Analyst consensus remains positive with 62.5% buy ratings, though recent news highlights concerns about oil price exposure and reduced traffic forecasts.

The outlook balances strong profitability and market position against near-term headwinds from fuel costs and competitive pricing. Investment opportunity lies in Ryanair's industry-leading efficiency and potential market share gains during industry consolidation. Key risks include unhedged fuel costs, winter capacity cuts, and macroeconomic sensitivity. The stock's current valuation at 13.04 P/E appears reasonable if the company can maintain its earnings trajectory amid industry challenges.

Twist Bioscience Corp

Twist Bioscience (TWST) trades at $128.06, up 2.68% with a bearish technical signal despite recent AI-driven momentum. The company shows strong revenue growth (2025: $377M, 2026: $432M projected) but continues to report significant losses with negative net margins. Recent news highlights AI partnerships and a $300M stock offering, while analyst consensus remains predominantly bullish with 78.6% buy ratings.

TWST presents a high-risk growth opportunity with accelerating revenue but persistent profitability challenges. The stock's valuation appears stretched at P/S of 18.09, requiring successful execution on AI initiatives and path to EBITDA breakeven. Key risks include cash burn, competitive pressures, and dependence on emerging AI-driven drug discovery markets.

Returns comparison

Trailing returns across standard periods

Top news

Latest headlines on both assets

About Ryanair Holdings plc

Ryanair is the leading airline group by passenger numbers in Europe. The company employs a low-cost no-frills model to offer low fares to leisure customers on short-haul intra-European routes. In 2020, the most recent pre-pandemic fiscal year, the company carried 149 million passengers, utilizing a fleet of 467 Boeing 737 aircraft across its 1,800 routes. To keep costs low the company serves predominantly lower-cost secondary airports. The company generated sales of EUR 8.5 billion in fiscal 2020.

Read more on RYAAY

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST