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Compare Orion Office REIT Inc (ONL) vs Twist Bioscience Corp (TWST) Price & Performance

Orion Office REIT IncTrade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

Orion Office REIT Inc vs Twist Bioscience Corp — how do they compare? Orion Office REIT Inc trades at $2.2 (market cap $125.50M), while Twist Bioscience Corp trades at $153.4 (market cap $10.08B). The key difference: Twist Bioscience Corp is far larger — about 80.3× Orion Office REIT Inc's market cap, and Orion Office REIT Inc pays a 3.64% dividend while Twist Bioscience Corp pays none. Which is the better fit depends on your goals — on Pluang, investors hold Orion Office REIT Inc for 33 Days and Twist Bioscience Corp for 27 Days on average.

ONLTWST
Market Cap
$125.50M$10.08B
Volume
303,2764,229,037
Sector
Real EstateHealth
52-Week High
$3.00$205.00
52-Week Low
$1.93$25.45
Typical Hold Time
33 Days27 Days
Enterprise Value
$542.43M$10.01B
Dividend Yield
3.64%—

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Orion Office REIT Inc

ONL trades at $2.27, down 2.58% today, with a bearish technical signal from moving averages but bullish oscillators. The company shows declining revenue from $208M in 2022 to $148M in 2025, with persistent net losses widening to -$139M. Analyst consensus is split 50/50 buy/hold, while recent news highlights strategic portfolio repositioning and Q2 2026 earnings beat.

Outlook remains challenged by negative profitability and high debt levels, though low P/B of 0.2 suggests deep value. Key risks include office sector headwinds and cash flow volatility. Investment appeal hinges on successful execution of turnaround strategy amid weak fundamental trends.

Twist Bioscience Corp

TWST trades at $155.65, down 6.78% today, reflecting a bearish technical signal and recent earnings misses. Revenue growth is strong, rising to $376.57M in 2025, but profitability remains elusive with a net income margin of -31.66%. The company's partnership with Lilly TuneLab for AI-driven drug discovery has generated positive news flow, yet cash flow remains negative, and the stock trades at elevated valuation multiples like P/S of 22.01.

The outlook is mixed: strong analyst buy-side consensus (73% Buy) and strategic AI partnerships offer growth potential, but persistent losses, high cash burn, and bearish technicals pose significant risks. Investors face a trade-off between long-term innovation prospects and near-term financial instability.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

ONL

No sentiment data available yet.

TWST
37% Buy63% Sell
Avg holding period · 27 Days

Top news

Latest headlines on both assets

About Orion Office REIT Inc

Orion Office REIT Inc is a internally-managed REIT engaged in the ownership, acquisition, and management of a diversified portfolio of mission-critical and headquarters office buildings located in high quality suburban markets across the U.S. and leased primarily on a single-tenant net lease basis to creditworthy clients.

Read more on ONL →

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST →