Medpace Holdings Inc vs Vanguard S&P 500 ETF — how do they compare? Medpace Holdings Inc trades at $530 (market cap $15.08B), while Vanguard S&P 500 ETF trades at $687.69. The key difference: Vanguard S&P 500 ETF is trading nearer its 52-week high, Medpace Holdings Inc nearer its low. Which is the better fit depends on your goals.
| MEDP | VOO | |
|---|---|---|
Market Cap | $15.08B | — |
Sector | Technology | Broad Market / Factor |
52-Week High | $620.59 | $698.29 |
52-Week Low | $308.88 | $571.45 |
Enterprise Value | $14.55B | — |
Signals from Pluang's Aura AI — not financial advice
MEDP trades at $527.93, down 1.82% on the day, with a neutral technical signal and mixed oscillators. The stock shows strong profitability with a 17.19% net margin and 77.25% ROE, though valuations are elevated with a P/E of 33.22. Recent quarters have consistently beaten EPS estimates, but a class action lawsuit filed in June 2026 adds uncertainty. Revenue is projected to grow to $2.7B in 2026, while cash flow trends improve from negative to positive net cash flow.
The outlook is cautious due to high valuation and legal overhangs, but fundamental strength in earnings and backlog quality provides support. Analyst consensus is mixed with a $497 price target below current levels, indicating limited near-term upside. Key risks include lawsuit outcomes and competitive pressures in the CRO sector.
VOO, the Vanguard S&P 500 ETF, trades at $682.20, down slightly by 0.14% over 24 hours. Technical indicators show a bearish trend with moving averages signaling caution, though oscillators are neutral. The ETF recently surpassed $1.0 trillion in assets under management, reflecting strong institutional confidence. A dividend of $1.96 is scheduled for payment on June 30, 2026.
The outlook for VOO is mixed; its low-cost, diversified exposure to the S&P 500 offers long-term growth potential, but current technical weakness and elevated market valuations pose near-term risks. Investors should weigh the ETF's historical resilience against potential volatility from economic shifts or sector rotations.
Trailing returns across standard periods
Latest headlines on both assets
Medpace Holdings, Inc. is a full-service clinical contract research organization (CRO) that provides comprehensive and scientifically-driven clinical development services to the biotechnology, pharmaceutical, and medical device industries. The company specializes in conducting global clinical trials for new drug and medical device approvals. Medpace's model emphasizes therapeutic expertise and a highly integrated approach to accelerate the clinical development process for its clients.
Read more on MEDP →VOO is a foundational ETF that tracks the S&P 500 Index, providing exposure to 500 of the largest and most established companies in the United States. Renowned for its ultra-low expense ratio and tax efficiency, it serves as a core building block for long-term investors seeking to capture the total return of the U.S. large-cap market in a single, highly liquid vehicle.
Read more on VOO →