Medpace Holdings Inc vs Upwork Inc — how do they compare? Medpace Holdings Inc trades at $519.93 (market cap $15.08B), while Upwork Inc trades at $9.29 (market cap $1.15B). The key difference: Medpace Holdings Inc is far larger — about 13.1× Upwork Inc's market cap, and Medpace Holdings Inc is trading nearer its 52-week high, Upwork Inc nearer its low. Which is the better fit depends on your goals.
| MEDP | UPWK | |
|---|---|---|
Market Cap | $15.08B | $1.15B |
Sector | Technology | Industrials |
52-Week High | $620.59 | $22.11 |
52-Week Low | $308.88 | $7.84 |
Enterprise Value | $14.55B | $952.17M |
Signals from Pluang's Aura AI — not financial advice
MEDP trades at $527.93, down 1.82% today, with a bullish technical outlook supported by moving averages. The company demonstrates strong profitability with 17.19% net margins and 77.25% ROE, though valuation ratios appear elevated with a P/E of 33.83. Recent earnings have consistently beaten expectations, and cash flow is projected to improve significantly in 2026. However, the stock faces headwinds from ongoing class action lawsuits and mixed analyst sentiment with 73.69% hold ratings.
MEDP presents a mixed investment case with strong fundamental performance offset by legal overhangs and premium valuation. The company's consistent earnings beats and projected cash flow improvement support upside potential, but investors should weigh the legal risks and cautious analyst stance against the robust operational metrics.
UPWK trades at $9.33, up 2.98% today, with a neutral technical signal and mixed earnings history including recent EPS misses. Revenue grew to $787.78M in 2025 with strong profitability margins (net margin 13.81%), but cash flow turned negative. Analyst consensus is a Buy with a $10.67 target, though legal investigations and competitive pressures pose headwinds.
The stock offers value with low P/E (11.19) and EV/EBITDA (5.96), but risks include ongoing fraud probes and gig economy volatility. Upside depends on execution amid AI integration initiatives, while downside is cushioned by solid balance sheet liquidity.
Trailing returns across standard periods
Medpace Holdings, Inc. is a full-service clinical contract research organization (CRO) that provides comprehensive and scientifically-driven clinical development services to the biotechnology, pharmaceutical, and medical device industries. The company specializes in conducting global clinical trials for new drug and medical device approvals. Medpace's model emphasizes therapeutic expertise and a highly integrated approach to accelerate the clinical development process for its clients.
Read more on MEDP →Upwork Inc is a United States-based company that operates an online marketplace that enables businesses to find and work with highly-skilled independent professionals. The develops platform for hiring and freelancing purposes. Its products offering include Upwork Basic, Upwork Plus, Upwork Business, Upwork Enterprise, and Upwork Payroll. The business generates revenue from Talent and Clients across the USA, India, the Philippines and the rest of the world. Substantial income is derived from providing services to Clients.
Read more on UPWK →