McKesson Corporation vs Old Dominion Freight Line Inc — how do they compare? McKesson Corporation trades at $832.45 (market cap $97.35B), while Old Dominion Freight Line Inc trades at $231.38 (market cap $48.20B). The key difference: McKesson Corporation is far larger — about 2× Old Dominion Freight Line Inc's market cap, and Old Dominion Freight Line Inc pays the higher dividend (0.5%). Which is the better fit depends on your goals.
| MCK | ODFL | |
|---|---|---|
Market Cap | $97.35B | $48.20B |
Sector | Health | Industrials |
52-Week High | $995.69 | $248.73 |
52-Week Low | $659.01 | $126.29 |
Enterprise Value | $101.98B | $47.95B |
Dividend Yield | 0.39% | 0.5% |
Signals from Pluang's Aura AI — not financial advice
McKesson Corporation (MCK) trades at $831.60, down 1.16% on the day, with a bullish technical signal and positive earnings momentum after beating estimates for three consecutive quarters. The stock shows strong analyst support with an 80% buy rating and a consensus price target of $932.83, implying potential upside. Revenue growth is robust, reaching $359.05 billion in 2025, though net margins remain thin at 1.18%. Cash flow from operations improved to $6.09 billion in 2025, supporting financial stability.
The outlook for MCK is positive, driven by earnings beats, analyst optimism, and solid cash generation. Key opportunities include growth in specialty pharma and oncology services. Risks involve policy uncertainties, competitive pressures, and execution challenges. The stock's current price near key support at $829 suggests a critical level for near-term direction.
Old Dominion Freight Line (ODFL) trades at $231.79, down 0.88% on the day, with a bullish technical signal supported by moving averages. The company maintains strong profitability with an 18.46% net income margin and has beaten earnings estimates for three consecutive quarters. Recent news highlights improved LTL metrics and a quarterly dividend of $0.29 per share, though valuation remains elevated with a P/E of 48.82.
ODFL's outlook is supported by operational excellence and a debt-light balance sheet, but high valuation and competitive pressures from players like Amazon pose risks. Analyst consensus is mixed with a $233.67 price target, suggesting limited upside from current levels amid economic uncertainties in the freight sector.
Trailing returns across standard periods
McKesson is a leading wholesaler of branded, generic, and specialty pharmaceutical products to pharmacies (retail chains, independent, and mail order), hospitals networks, and healthcare providers. Along with AmerisourceBergen and Cardinal Health, the three account for well over 90% of the U.S. pharmaceutical wholesale industry. McKesson is currently divesting from its pharmaceutical wholesale and distribution in Europe and Canada in order to redeploy capital to strategic growth areas in the U.S. (oncology network and ecosystem, and biopharma services). Additionally, the company supplies medical-surgical products and equipment to healthcare facilities and provides a variety of technology solutions for pharmacies.
Read more on MCK →Old Dominion Freight Line is the fourth-largest less-than-truckload carrier in the United States, with more than 240 service centers and 9,200-plus tractors. OD is by far one of the most disciplined and efficient providers in the trucking industry, and its profitability and capital returns stand head and shoulders above its peers. Strategic initiatives revolve around increasing network density through market share gains and maintaining industry-leading service via consistent infrastructure investment.
Read more on ODFL →