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Compare Intuitive Surgical, Inc. (ISRG) vs 22nd Century Group Inc (XXII) Price & Performance

Intuitive Surgical, Inc.Trade
22nd Century Group IncTrade

Price performance (Past 24H)

Key statistics

Intuitive Surgical, Inc. vs 22nd Century Group Inc — how do they compare? Intuitive Surgical, Inc. trades at $423.96 (market cap $146.76B), while 22nd Century Group Inc trades at $0.81 (market cap $621.67K). The key difference: Intuitive Surgical, Inc. is far larger — about 236073.8× 22nd Century Group Inc's market cap, and Intuitive Surgical, Inc. is trading nearer its 52-week high, 22nd Century Group Inc nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Intuitive Surgical, Inc. for 84 Days and 22nd Century Group Inc for 32 Days on average.

ISRGXXII
Market Cap
$146.76B$621.67K
Volume
2,529,81445,625
Sector
HealthConsumer Staples
52-Week High
$592.85$483.00
52-Week Low
$332.02$0.80
Typical Hold Time
84 Days32 Days
Enterprise Value
$141.54B-$3.69M

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Intuitive Surgical, Inc.

Intuitive Surgical (ISRG) trades at $415.41, up 0.21% today, with a bullish technical signal from moving averages and neutral oscillators. The company reported strong Q2 2026 earnings, beating estimates with EPS of $2.80, and has shown consistent revenue growth, reaching $10.06B in 2025. Analyst consensus is strongly bullish with a $480.78 price target, though the stock faces headwinds from slower procedure growth in some markets.

The outlook for ISRG remains positive due to its dominant position in robotic surgery, expanding international presence, and high recurring revenue. Key risks include competitive pressures, regulatory hurdles, and economic sensitivity affecting procedure volumes. With solid fundamentals and analyst support, the stock offers growth potential, but investors should monitor execution against these risks.

22nd Century Group Inc

XXII trades at $0.8116, down 8.96% in the last session, with a bearish technical signal from moving averages. The company shows negative profitability metrics including -76.01% net income margin and -284.5% ROE, though valuation ratios appear low with P/S of 0.08 and P/B of 0.03. Recent news highlights regulatory progress in reduced-nicotine tobacco initiatives in France and Europe.

While analyst consensus is 75% buy with a $1,240 price target suggesting significant upside, fundamental challenges persist with consecutive earnings misses and negative cash flow from operations. The stock faces execution risk in commercializing its reduced-nicotine platform amid ongoing losses.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

ISRG
92% Buy8% Sell
Avg holding period · 84 Days
XXII
100% Buy0% Sell
Avg holding period · 32 Days

Top news

Latest headlines on both assets

About Intuitive Surgical, Inc.

Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.

Read more on ISRG →

About 22nd Century Group Inc

22nd Century Group is a plant biotechnology company that uses genetic engineering and gene editing to control the levels of nicotine in tobacco plants. Its flagship product line, VLN®, is the first and only combustible cigarette authorized by the FDA as a Modified Risk Tobacco Product (MRTP), containing 95% less nicotine than traditional cigarettes to help adult smokers smoke less.

Read more on XXII →