Compare Intuitive Surgical, Inc. (ISRG) vs Vanguard S&P 500 ETF (VOO) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Intuitive Surgical, Inc. vs Vanguard S&P 500 ETF — how do they compare? Intuitive Surgical, Inc. trades at $399.12 (market cap $141.75B), while Vanguard S&P 500 ETF trades at $709.9. The key difference: Vanguard S&P 500 ETF is trading nearer its 52-week high, Intuitive Surgical, Inc. nearer its low. Which is the better fit depends on your goals.
| ISRG | VOO | |
|---|---|---|
Market Cap | $141.75B | — |
Sector | Health | Broad Market / Factor |
52-Week High | $592.85 | $710.71 |
52-Week Low | $332.02 | $580.93 |
Enterprise Value | $136.53B | — |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Intuitive Surgical (ISRG) trades at $393.38, up 3.85% on the day, with a bullish technical signal and strong earnings momentum, having beaten EPS estimates for three consecutive quarters. The stock exhibits premium valuation metrics, including a P/E of 46.01 and P/S of 13.08, supported by robust revenue growth, which reached $10.06B in 2025, and high net income margins of 28.45%. Recent news highlights analyst upgrades and optimism around the da Vinci 5 system's adoption.
The outlook remains positive given durable demand and innovation, but risks include heightened competition and valuation sensitivity. Wall Street consensus is bullish with a $518.10 price target, implying significant upside, though investors should weigh premium multiples against growth sustainability and competitive pressures in the medtech space.
VOO, the Vanguard S&P 500 ETF, trades at $710.19, down slightly by 0.06% today, with a bullish technical signal from moving averages but neutral oscillators. The ETF is near its pivot point of $709, with immediate resistance at $711. Recent news highlights the S&P 500 at record highs, with JPMorgan raising its year-end target to 8,000, citing strong earnings and AI-driven growth, while some caution emerges from overbought signals and high valuations.
The outlook remains positive given institutional bullishness and AI tailwinds, but risks include market overvaluation, potential pullbacks from overbought conditions, and sensitivity to inflation data. Long-term investors may benefit from dollar-cost averaging, though short-term volatility warrants caution amid elevated sentiment and technical indicators signaling near-term exhaustion.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.
Read more on ISRG →About Vanguard S&P 500 ETF
VOO is a foundational ETF that tracks the S&P 500 Index, providing exposure to 500 of the largest and most established companies in the United States. Renowned for its ultra-low expense ratio and tax efficiency, it serves as a core building block for long-term investors seeking to capture the total return of the U.S. large-cap market in a single, highly liquid vehicle.
Read more on VOO →
