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Compare Intuitive Surgical, Inc. (ISRG) vs Twilio Inc (TWLO) Price & Performance

Intuitive Surgical, Inc.Trade
Twilio IncTrade

Price performance (Past 24H)

Key statistics

Intuitive Surgical, Inc. vs Twilio Inc — how do they compare? Intuitive Surgical, Inc. trades at $401.39 (market cap $141.75B), while Twilio Inc trades at $245.95 (market cap $39.31B). The key difference: Intuitive Surgical, Inc. is far larger — about 3.6× Twilio Inc's market cap, and Twilio Inc is trading nearer its 52-week high, Intuitive Surgical, Inc. nearer its low. Which is the better fit depends on your goals.

ISRGTWLO
Market Cap
$141.75B$39.31B
Sector
HealthTechnology
52-Week High
$592.85$255.95
52-Week Low
$332.02$95.23
Enterprise Value
$136.53B$37.72B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Intuitive Surgical, Inc.

Intuitive Surgical (ISRG) trades at $401.46, up 2.05% today, with strong quarterly earnings beats and bullish analyst consensus. The stock shows robust revenue growth, expanding margins, and solid cash flow, supported by the da Vinci 5 system adoption. Technical indicators are mixed, with RSI signaling overbought conditions but moving averages bullish.

Outlook remains positive due to durable demand and innovation, though high valuation and competition pose risks. Upside to the $518.10 consensus target offers potential, but investors should weigh premium multiples against growth sustainability.

Twilio Inc

Twilio (TWLO) trades at $247.64, down 0.97% on the day but near its 52-week high, with a bullish technical outlook supported by moving averages. The company reported strong Q2 2026 results, beating EPS estimates with $1.47 actual vs. $1.32 expected, and raised full-year revenue growth guidance to 18-18.5%. Fundamentals show improving profitability, with net income margin reaching 20.62% in 2026, and positive cash flow trends.

The outlook is positive due to accelerating revenue growth and robust free cash flow generation, but risks include high valuation multiples like a P/E of 35.35 and competitive pressures in cloud communications. Analyst consensus is strongly bullish with a $266.31 price target, suggesting potential upside from current levels.

Returns comparison

Trailing returns across standard periods

Top news

Latest headlines on both assets

About Intuitive Surgical, Inc.

Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.

Read more on ISRG

About Twilio Inc

Twilio Inc. is a cloud-based communication platform-as-a-service company offering communication building blocks that allow for a fully customized customer engagement experience spanning voice, video, chat, and SMS messaging. It does this through various application programming interfaces, or APIs, and prebuilt solution applications aimed at improving customer engagement. The company leverages its Super Network, a global network of carrier relationships, to facilitate high-speed, cost-effective communication.

Read more on TWLO