Compare Intuitive Surgical, Inc. (ISRG) vs Twilio Inc (TWLO) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Intuitive Surgical, Inc. vs Twilio Inc — how do they compare? Intuitive Surgical, Inc. trades at $403.98 (market cap $141.75B), while Twilio Inc trades at $246.28 (market cap $39.31B). The key difference: Intuitive Surgical, Inc. is far larger — about 3.6× Twilio Inc's market cap, and Twilio Inc is trading nearer its 52-week high, Intuitive Surgical, Inc. nearer its low. Which is the better fit depends on your goals.
| ISRG | TWLO | |
|---|---|---|
Market Cap | $141.75B | $39.31B |
Sector | Health | Technology |
52-Week High | $592.85 | $255.95 |
52-Week Low | $332.02 | $95.23 |
Enterprise Value | $136.53B | $37.72B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Intuitive Surgical (ISRG) trades at $403.95, up 2.69% on the day, reflecting strong momentum. The stock exhibits bullish technical signals with support at $398 and resistance at $403. Fundamentally, revenue grew to $10.06B in 2025 with a net income margin of 28.45%, though valuation ratios like a P/E of 46.01 suggest premium pricing. Recent quarters show consistent earnings beats, with Q2 2026 EPS of $2.80 exceeding expectations. News highlights analyst upgrades and robust adoption of the da Vinci 5 system.
Outlook remains positive driven by innovation and market expansion, but high valuation and competitive pressures pose risks. The consensus price target of $518.10 implies significant upside, supported by 68% buy ratings from analysts. Key risks include reliance on U.S. procedure growth and rising competition from Medtronic and Johnson & Johnson. Long-term growth prospects appear solid if execution continues.
Twilio (TWLO) trades at $247.10, down 1.18% on the day, but remains near its 52-week high after a strong rally driven by Q2 2026 earnings beats and raised guidance. The stock shows bullish technical signals with support at $246 and resistance at $259. Revenue growth accelerated to 22% year-over-year in Q2, with net income turning positive in 2025 after years of losses, reflecting improved profitability and cash flow generation.
Outlook is positive with Wall Street consensus Buy rating and $266.31 price target, though high valuation multiples (P/E 35.35) and overbought RSI levels suggest near-term consolidation risk. Key opportunities include AI-driven growth and expanding free cash flow margins, while risks involve competitive pressures and execution on guidance.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.
Read more on ISRG →About Twilio Inc
Twilio Inc. is a cloud-based communication platform-as-a-service company offering communication building blocks that allow for a fully customized customer engagement experience spanning voice, video, chat, and SMS messaging. It does this through various application programming interfaces, or APIs, and prebuilt solution applications aimed at improving customer engagement. The company leverages its Super Network, a global network of carrier relationships, to facilitate high-speed, cost-effective communication.
Read more on TWLO →
