Compare Intuitive Surgical, Inc. (ISRG) vs Twilio Inc (TWLO) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Intuitive Surgical, Inc. vs Twilio Inc — how do they compare? Intuitive Surgical, Inc. trades at $423.96 (market cap $146.76B), while Twilio Inc trades at $289.47 (market cap $42.35B). The key difference: Intuitive Surgical, Inc. is far larger — about 3.5× Twilio Inc's market cap, and Twilio Inc is trading nearer its 52-week high, Intuitive Surgical, Inc. nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Intuitive Surgical, Inc. for 84 Days and Twilio Inc for 56 Days on average.
| ISRG | TWLO | |
|---|---|---|
Market Cap | $146.76B | $42.35B |
Volume | 2,529,814 | 1,862,642 |
Sector | Health | Technology |
52-Week High | $592.85 | $301.27 |
52-Week Low | $332.02 | $106.23 |
Typical Hold Time | 84 Days | 56 Days |
Enterprise Value | $141.54B | $40.76B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Intuitive Surgical (ISRG) trades at $423.96, up 2.28% with strong bullish momentum. The stock shows robust fundamentals with 2025 revenue reaching $10.06B and net income of $2.86B, maintaining 28.45% net margins. Recent quarters consistently beat EPS estimates, while technical indicators signal bullish moving averages. Analyst consensus remains strongly positive with 70% buy ratings and $480.78 price target, representing 13% upside potential.
ISRG's leadership in robotic surgery and expanding international presence in India and Japan provide growth catalysts, though China weakness and competitive pressures present risks. The stock's premium valuation (P/E 47.64) reflects high growth expectations, requiring continued execution. Current levels near resistance at $427 may test near-term momentum ahead of Q3 earnings.
Twilio (TWLO) trades at $275.77, up 1.01% with a bullish technical signal. The company shows strong fundamental improvement with revenue growing from $3.8B in 2022 to $5.1B in 2025, achieving positive net income of $34M after years of losses. Recent Q2 2026 earnings beat expectations with EPS of $1.47 versus $1.32 expected. The stock's inclusion in the S&P 500 index effective October 6, 2026, provides institutional validation and potential index fund inflows.
Twilio presents a compelling growth story with accelerating revenue and profitability, though valuation remains elevated at P/E 38.09. Key risks include competitive pressures in customer engagement software and execution challenges in maintaining growth momentum. Analyst consensus remains strongly bullish with 77% buy ratings, though the current price exceeds the $254.65 consensus target, suggesting near-term caution may be warranted despite positive long-term prospects.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Investor sentiment on Pluang
What Pluang investors did over the last 30 days
Investor sentiment on Pluang
What Pluang investors did over the last 30 days
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.
Read more on ISRG →About Twilio Inc
Twilio Inc. is a cloud-based communication platform-as-a-service company offering communication building blocks that allow for a fully customized customer engagement experience spanning voice, video, chat, and SMS messaging. It does this through various application programming interfaces, or APIs, and prebuilt solution applications aimed at improving customer engagement. The company leverages its Super Network, a global network of carrier relationships, to facilitate high-speed, cost-effective communication.
Read more on TWLO →
