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Compare Intuitive Surgical, Inc. (ISRG) vs Novavax Inc (NVAX) Price & Performance

Intuitive Surgical, Inc.Trade
Novavax IncTrade

Price performance (Past 24H)

Key statistics

Intuitive Surgical, Inc. vs Novavax Inc — how do they compare? Intuitive Surgical, Inc. trades at $425.1 (market cap $146.76B), while Novavax Inc trades at $12.6 (market cap $1.82B). The key difference: Intuitive Surgical, Inc. is far larger — about 80.6× Novavax Inc's market cap, and Novavax Inc is trading nearer its 52-week high, Intuitive Surgical, Inc. nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Intuitive Surgical, Inc. for 84 Days and Novavax Inc for 59 Days on average.

ISRGNVAX
Market Cap
$146.76B$1.82B
Volume
2,529,8146,198,505
Sector
HealthHealth
52-Week High
$592.85$12.56
52-Week Low
$332.02$6.22
Typical Hold Time
84 Days59 Days
Enterprise Value
$141.54B$1.39B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Intuitive Surgical, Inc.

Intuitive Surgical (ISRG) trades at $414.52, up 2.41% today, with strong bullish technical signals from moving averages. The company demonstrates robust fundamentals with revenue growth from $6.2B in 2022 to $10.1B in 2025 and net income margin expanding to 28.45%. Recent quarterly earnings have consistently beaten expectations, with Q2 2026 EPS of $2.80 surpassing the $2.48 forecast.

ISRG maintains a dominant position in robotic surgery with expanding international growth, though valuation multiples remain elevated with a P/E of 47.64. Analyst consensus is strongly bullish with a $480.78 price target representing 16% upside potential. Key risks include competitive pressures and international market volatility, particularly in China.

Novavax Inc

Novavax (NVAX) trades at $12.41, up 10.61% today, with strong technical momentum and bullish moving average signals. The company shows mixed fundamentals with a low P/E of 3.14 and EV/EBITDA of 1.72, but negative net income margin of -59.87% and negative shareholder equity. Recent earnings beats and FDA approvals for updated COVID-19 vaccines provide near-term catalysts.

Investment outlook remains speculative with significant execution risks despite analyst optimism (74% buy ratings). The company's pivot to Matrix-M adjuvant licensing and partnership model offers growth potential, but negative cash flow and high debt levels pose substantial financial risk. Stock appears undervalued on some metrics but requires careful risk management.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

ISRG
25% Buy75% Sell
Avg holding period · 84 Days
NVAX
59% Buy41% Sell
Avg holding period · 59 Days

Top news

Latest headlines on both assets

About Intuitive Surgical, Inc.

Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.

Read more on ISRG →

About Novavax Inc

Novavax, Inc. is a clinical stage biotechnology company. The Company creates novel vaccines to address a broad range of infectious diseases worldwide using proprietary virus-like particle (VLP) technology.

Read more on NVAX →