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Compare Intuitive Surgical, Inc. (ISRG) vs Neurocrine Biosciences Inc (NBIX) Price & Performance

Intuitive Surgical, Inc.Trade
Neurocrine Biosciences IncTrade

Price performance (Past 24H)

Key statistics

Intuitive Surgical, Inc. vs Neurocrine Biosciences Inc — how do they compare? Intuitive Surgical, Inc. trades at $422.99 (market cap $146.76B), while Neurocrine Biosciences Inc trades at $141.74 (market cap $14.36B). The key difference: Intuitive Surgical, Inc. is far larger — about 10.2× Neurocrine Biosciences Inc's market cap, and Intuitive Surgical, Inc. is more actively traded (2,529,814 versus 1,237,180). Which is the better fit depends on your goals — on Pluang, investors hold Intuitive Surgical, Inc. for 84 Days and Neurocrine Biosciences Inc for 23 Days on average.

ISRGNBIX
Market Cap
$146.76B$14.36B
Volume
2,529,8141,237,180
Sector
HealthHealth
52-Week High
$592.85$185.50
52-Week Low
$332.02$123.10
Typical Hold Time
84 Days23 Days
Enterprise Value
$141.54B$14.37B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Intuitive Surgical, Inc.

Intuitive Surgical (ISRG) trades at $414.52, up 2.41% today, with strong bullish technical signals from moving averages. The company demonstrates robust fundamentals with revenue growth from $6.2B in 2022 to $10.1B in 2025 and net income margin expanding to 28.45%. Recent quarterly earnings have consistently beaten expectations, with Q2 2026 EPS of $2.80 surpassing the $2.48 forecast.

ISRG maintains a dominant position in robotic surgery with expanding international growth, though valuation multiples remain elevated with a P/E of 47.64. Analyst consensus is strongly bullish with a $480.78 price target representing 16% upside potential. Key risks include competitive pressures and international market volatility, particularly in China.

Neurocrine Biosciences Inc

Neurocrine Biosciences (NBIX) trades at $141.69, down 1.24% on the day, with a bearish technical signal from moving averages. Fundamentally, the company shows strong profitability with a 20.91% net income margin and consistent earnings beats, including a significant Q2 2026 beat. Recent news highlights pipeline advancements and executive appointments, while analyst sentiment remains overwhelmingly positive.

The outlook for NBIX is supported by robust fundamentals and strong analyst buy ratings, but near-term price action is challenged by technical bearishness. Key opportunities include product diversification and pipeline growth, while risks involve execution of expansion plans and potential pricing pressures on key products like INGREZZA.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

ISRG
25% Buy75% Sell
Avg holding period · 84 Days
NBIX

No sentiment data available yet.

Top news

Latest headlines on both assets

About Intuitive Surgical, Inc.

Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.

Read more on ISRG →

About Neurocrine Biosciences Inc

Neurocrine Biosciences, Inc. is a biopharmaceutical company focused on discovering, developing, and commercializing innovative treatments for neurological, endocrine, and psychiatric disorders. The company's portfolio targets conditions such as tardive dyskinesia, endometriosis, and Parkinson's disease. NBIX leverages its expertise in neurobiology and small-molecule drug development to address diseases with significant unmet medical needs.

Read more on NBIX →