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Compare Intuitive Surgical, Inc. (ISRG) vs McKesson Corporation (MCK) Price & Performance

Intuitive Surgical, Inc.Trade
McKesson CorporationTrade

Price performance (Past 24H)

Key statistics

Intuitive Surgical, Inc. vs McKesson Corporation — how do they compare? Intuitive Surgical, Inc. trades at $424.55 (market cap $146.76B), while McKesson Corporation trades at $937.1 (market cap $108.46B). The key difference: Intuitive Surgical, Inc. is the larger of the two by market cap, and McKesson Corporation pays a 0.4% dividend while Intuitive Surgical, Inc. pays none. Which is the better fit depends on your goals — on Pluang, investors hold Intuitive Surgical, Inc. for 84 Days and McKesson Corporation for 74 Days on average.

ISRGMCK
Market Cap
$146.76B$108.46B
Volume
2,529,814712,607
Sector
HealthHealth
52-Week High
$592.85$995.69
52-Week Low
$332.02$725.17
Typical Hold Time
84 Days74 Days
Enterprise Value
$141.54B$115.00B
Dividend Yield
—0.4%

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Intuitive Surgical, Inc.

Intuitive Surgical (ISRG) trades at $424.58, up 2.43% with strong bullish momentum. The stock shows robust fundamentals with revenue growing from $6.2B in 2022 to $10.1B in 2025 and net profit margins exceeding 28%. Recent earnings consistently beat expectations, with Q2 2026 EPS of $2.80 surpassing the $2.48 forecast. Technical indicators show bullish moving averages with support at $410 and resistance at $419. Analyst consensus remains strongly positive with 70% buy ratings and a $480.78 price target.

ISRG maintains a dominant position in robotic surgery with expanding international growth offsetting China headwinds. The primary investment opportunity lies in continued procedure growth and da Vinci 5 adoption, though risks include competitive pressures and affordability concerns. With strong cash flow generation and institutional support, the stock presents upside potential despite premium valuations.

McKesson Corporation

McKesson Corporation (MCK) trades at $937.98, up 3.04% with strong technical momentum and bullish analyst sentiment. The stock shows consistent earnings beats with Q2 2026 EPS of $9.93 exceeding expectations of $9.56. Recent positive developments include the CVS Health partnership extension through 2032 and raised full-year guidance. Revenue growth remains robust at $359.05 billion for 2025, though net margins are thin at 1.12%.

The outlook remains positive with 81% analyst buy ratings and a $956.43 consensus target. Key risks include margin pressure from drug pricing dynamics and policy uncertainty. Strong cash flow generation ($6.09B operating cash flow) supports the dividend and growth initiatives, while technical indicators show the stock testing resistance near $938.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

ISRG
92% Buy8% Sell
Avg holding period · 84 Days
MCK
100% Buy0% Sell
Avg holding period · 74 Days

Top news

Latest headlines on both assets

About Intuitive Surgical, Inc.

Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.

Read more on ISRG →

About McKesson Corporation

McKesson is a leading wholesaler of branded, generic, and specialty pharmaceutical products to pharmacies (retail chains, independent, and mail order), hospitals networks, and healthcare providers. Along with AmerisourceBergen and Cardinal Health, the three account for well over 90% of the U.S. pharmaceutical wholesale industry. McKesson is currently divesting from its pharmaceutical wholesale and distribution in Europe and Canada in order to redeploy capital to strategic growth areas in the U.S. (oncology network and ecosystem, and biopharma services). Additionally, the company supplies medical-surgical products and equipment to healthcare facilities and provides a variety of technology solutions for pharmacies.

Read more on MCK →