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Compare Iris Energy Limited (IREN) vs Twist Bioscience Corp (TWST) Price & Performance

Iris Energy LimitedTrade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

Iris Energy Limited vs Twist Bioscience Corp — how do they compare? Iris Energy Limited trades at $36.59 (market cap $14.07B), while Twist Bioscience Corp trades at $152.84 (market cap $10.08B). The key difference: Iris Energy Limited is the larger of the two by market cap, and Twist Bioscience Corp is trading nearer its 52-week high, Iris Energy Limited nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Iris Energy Limited for 28 Days and Twist Bioscience Corp for 27 Days on average.

IRENTWST
Market Cap
$14.07B$10.08B
Volume
54,492,4604,229,037
Sector
TechnologyHealth
52-Week High
$76.41$205.00
52-Week Low
$29.31$25.45
Typical Hold Time
28 Days27 Days
Enterprise Value
$16.02B$10.01B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Iris Energy Limited

IREN trades at $38.69, down 6.27% today, amid a bearish technical trend and recent earnings misses. The company is aggressively pivoting from Bitcoin mining to AI infrastructure, securing multi-billion dollar contracts, but faces ballooning losses with a net income margin of -99.38% in 2026. Analyst consensus remains strongly bullish with a $81 price target, highlighting long-term revenue potential from AI demand, yet near-term execution and profitability challenges weigh on investor sentiment.

Outlook hinges on successful execution of AI expansion and cost management; opportunities include massive contracted revenue growth, but risks involve high capital burn, intense competition, and persistent negative earnings. The stock offers significant upside if targets are met, but volatility is expected amid transformative shifts.

Twist Bioscience Corp

TWST trades at $155.65, down 6.78% today, reflecting a bearish technical signal and recent earnings misses. Revenue growth is strong, rising to $376.57M in 2025, but profitability remains elusive with a net income margin of -31.66%. The company's partnership with Lilly TuneLab for AI-driven drug discovery has generated positive news flow, yet cash flow remains negative, and the stock trades at elevated valuation multiples like P/S of 22.01.

The outlook is mixed: strong analyst buy-side consensus (73% Buy) and strategic AI partnerships offer growth potential, but persistent losses, high cash burn, and bearish technicals pose significant risks. Investors face a trade-off between long-term innovation prospects and near-term financial instability.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IREN
86% Buy14% Sell
Avg holding period · 28 Days
TWST
37% Buy63% Sell
Avg holding period · 27 Days

Top news

Latest headlines on both assets

About Iris Energy Limited

Iris Energy is a next-generation data center company that powers Bitcoin mining and AI workloads using 100% renewable energy. It focuses on building sustainable infrastructure for the global digital economy.

Read more on IREN →

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST →