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Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Valero Energy Corporation (VLO) Price & Performance

Ionis Pharmaceuticals Inc. Common StockTrade
Valero Energy CorporationTrade

Price performance (Past 24H)

Key statistics

Ionis Pharmaceuticals Inc. Common Stock vs Valero Energy Corporation — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $42.5 (market cap $7.04B), while Valero Energy Corporation trades at $460.63 (market cap $131.43B). The key difference: Valero Energy Corporation is far larger — about 18.7× Ionis Pharmaceuticals Inc. Common Stock's market cap, and Valero Energy Corporation pays a 1.05% dividend while Ionis Pharmaceuticals Inc. Common Stock pays none. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Valero Energy Corporation for 57 Days on average.

IONSVLO
Market Cap
$7.04B$131.43B
Volume
2,977,4402,513,030
Sector
HealthEnergy
52-Week High
$86.50$459.78
52-Week Low
$42.38$156.39
Typical Hold Time
0 Days57 Days
Enterprise Value
$6.60B$134.90B
Dividend Yield
—1.05%

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ionis Pharmaceuticals Inc. Common Stock

No Aura AI signal available yet.

Valero Energy Corporation

Valero Energy (VLO) trades at $459.78, up 5.45% today, near its 52-week high. The stock exhibits strong bullish momentum with recent earnings beats and positive technical signals. Revenue declined to $122.69B in 2025, but net income margin improved to 5.17%. Analyst consensus is bullish with a 56.76% buy rating, though the current price exceeds the $408.10 consensus target. Recent news highlights institutional inflows and refining margin strength.

Outlook is positive due to earnings momentum and favorable sector trends, but risks include potential policy impacts on diesel exports and high valuation multiples. The stock's proximity to resistance at $460 suggests near-term consolidation may occur. Long-term growth depends on sustaining refining margins and cash flow generation.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IONS
100% Buy0% Sell
Avg holding period · 0 Days
VLO
94% Buy6% Sell
Avg holding period · 57 Days

Top news

Latest headlines on both assets

About Ionis Pharmaceuticals Inc. Common Stock

Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.

Read more on IONS →

About Valero Energy Corporation

Valero Energy is one of the largest independent refiners in the United States. It operates 14 refineries with a total throughput capacity of 3.2 million barrels a day in the United States, Canada, and the United Kingdom. Valero also owns 14 ethanol plants with capacity of 1.7 billion gallons of ethanol a year and holds a 50% stake in Diamond Green Diesel, which has capacity to produce 700 million gallons per year of renewable diesel.

Read more on VLO →