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Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Upstart Holdings Inc (UPST) Price & Performance

Ionis Pharmaceuticals Inc. Common StockTrade
Upstart Holdings IncTrade

Price performance (Past 24H)

Key statistics

Ionis Pharmaceuticals Inc. Common Stock vs Upstart Holdings Inc — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.2 (market cap $7.10B), while Upstart Holdings Inc trades at $22.56 (market cap $2.21B). The key difference: Ionis Pharmaceuticals Inc. Common Stock is far larger — about 3.2× Upstart Holdings Inc's market cap, and Upstart Holdings Inc is more actively traded (5,011,542 versus 2,027,457). Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Upstart Holdings Inc for 39 Days on average.

IONSUPST
Market Cap
$7.10B$2.21B
Volume
2,027,4575,011,542
Sector
HealthFinancials
52-Week High
$86.50$52.74
52-Week Low
$42.38$22.74
Typical Hold Time
0 Days39 Days
Enterprise Value
$6.66B$3.78B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ionis Pharmaceuticals Inc. Common Stock

No Aura AI signal available yet.

Upstart Holdings Inc

Upstart Holdings trades at $23.83, showing modest daily gains of 0.34% but remains in a bearish technical trend. The company reported mixed Q2 2026 earnings with $0.16 EPS missing expectations of $0.18, though revenue growth accelerated to $1.02 billion in 2025 with positive net income of $54 million. Recent news highlights partnership expansions into HELOC and auto lending while the stock faces pressure near 52-week lows.

Despite recent profitability improvements, Upstart faces execution risks with three consecutive earnings misses and negative operating cash flow. Analyst consensus remains divided with a $38.13 price target suggesting 60% upside potential, but high valuation multiples and competitive pressures in consumer lending warrant caution for investors.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IONS
100% Buy0% Sell
Avg holding period · 0 Days
UPST
100% Buy0% Sell
Avg holding period · 39 Days

About Ionis Pharmaceuticals Inc. Common Stock

Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.

Read more on IONS →

About Upstart Holdings Inc

Upstart Holdings Inc provides credit services. The company provides a proprietary, cloud-based, artificial intelligence lending platform. The platform aggregates consumer demand for loans and connects it to the network of Upstart AI-enabled bank partners. The revenue of the company is primarily comprised of fees paid by banks.

Read more on UPST →