Ionis Pharmaceuticals Inc. Common Stock vs Tilray Brands Inc — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $42.5 (market cap $7.04B), while Tilray Brands Inc trades at $3.1 (market cap $481.79M). The key difference: Ionis Pharmaceuticals Inc. Common Stock is far larger — about 14.6× Tilray Brands Inc's market cap, and Tilray Brands Inc is more actively traded (4,056,443 versus 2,977,440). Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Tilray Brands Inc for 31 Days on average.
| IONS | TLRY | |
|---|---|---|
Market Cap | $7.04B | $481.79M |
Volume | 2,977,440 | 4,056,443 |
Sector | Health | Health |
52-Week High | $86.50 | $16.80 |
52-Week Low | $42.38 | $3.14 |
Typical Hold Time | 0 Days | 31 Days |
Enterprise Value | $6.60B | $635.71M |
Signals from Pluang's Aura AI — not financial advice
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Tilray Brands (TLRY) trades at $3.27, down 2.68% on the day and near 52-week lows, with bearish technical signals dominating. The company reported $821 million in revenue for 2025 but posted a massive $2.19 billion net loss due to impairment charges. Recent earnings misses and negative cash flow from operations highlight ongoing profitability challenges despite analyst consensus pointing to significant upside potential.
TLRY presents a high-risk opportunity with substantial analyst price target divergence. While valuation metrics appear attractive (P/S 0.4x, P/B 0.3x), persistent losses and cash burn require careful monitoring. The stock's fate hinges on cannabis reform progress and the company's ability to achieve sustainable profitability amid competitive pressures.
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Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.
Read more on IONS →Tilray is a Canadian company that grows and sells medical and recreational cannabis. In 2021, Aphria acquired Tilray in a reverse merger and adopted the Tilray name. Most of its sales come from Canada and international medical cannabis exports, while its U.S. business focuses on CBD products and alcohol.
Read more on TLRY →