Ionis Pharmaceuticals Inc. Common Stock vs Sempra Energy — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.2 (market cap $7.10B), while Sempra Energy trades at $82.38 (market cap $53.61B). The key difference: Sempra Energy is far larger — about 7.6× Ionis Pharmaceuticals Inc. Common Stock's market cap, and Sempra Energy pays a 3.21% dividend while Ionis Pharmaceuticals Inc. Common Stock pays none. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Sempra Energy for 9 Days on average.
| IONS | SRE | |
|---|---|---|
Market Cap | $7.10B | $53.61B |
Volume | 2,027,457 | 3,549,235 |
Sector | Health | Utilities |
52-Week High | $86.50 | $99.75 |
52-Week Low | $42.38 | $76.90 |
Typical Hold Time | 0 Days | 9 Days |
Enterprise Value | $6.66B | $90.25B |
Dividend Yield | — | 3.21% |
Signals from Pluang's Aura AI — not financial advice
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Sempra Energy (SRE) trades at $82.37, up 0.6% on the day, with a mixed technical picture showing a bullish overall signal but bearish moving averages and oscillators. The company reported strong Q2 2026 earnings that beat expectations, with a net income margin of 16.83% and robust cash flow from operations of $5.4 billion in 2026. Recent developments include a 20-year LNG supply agreement with Petrobras and the opening of SoCalGas' new headquarters, signaling growth initiatives.
The outlook for SRE is positive, supported by analyst consensus with an 80.77% buy rating and a price target of $97.25, implying significant upside. Key opportunities include EPS growth guidance of 7–9% and strategic investments in Texas and LNG. Risks involve high capital expenditures, regulatory exposure, and interest rate sensitivity. The stock's current valuation at a P/E of 23.88 requires continued execution to justify further gains.
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Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.
Read more on IONS →Sempra is an energy infrastructure company with regulated utility and energy network businesses. Its operations include electric and gas utilities as well as energy infrastructure in North America.
Read more on SRE →