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Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Revolution Medicines Inc. Common Stock (RVMD) Price & Performance

Ionis Pharmaceuticals Inc. Common StockTrade
Revolution Medicines Inc. Common StockTrade

Price performance (Past 24H)

Key statistics

Ionis Pharmaceuticals Inc. Common Stock vs Revolution Medicines Inc. Common Stock — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.2 (market cap $7.10B), while Revolution Medicines Inc. Common Stock trades at $190 (market cap $41.53B). The key difference: Revolution Medicines Inc. Common Stock is far larger — about 5.8× Ionis Pharmaceuticals Inc. Common Stock's market cap, and Revolution Medicines Inc. Common Stock is trading nearer its 52-week high, Ionis Pharmaceuticals Inc. Common Stock nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Revolution Medicines Inc. Common Stock for 2 Days on average.

IONSRVMD
Market Cap
$7.10B$41.53B
Volume
2,027,4572,462,910
Sector
HealthHealth
52-Week High
$86.50$221.15
52-Week Low
$42.38$49.56
Typical Hold Time
0 Days2 Days
Enterprise Value
$6.66B$38.24B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ionis Pharmaceuticals Inc. Common Stock

No Aura AI signal available yet.

Revolution Medicines Inc. Common Stock

Revolution Medicines (RVMD) trades at $188.44, down 2.84% on the day, amid a bearish technical signal. The company reported no revenue in 2025, with a net loss of $1.13 billion, and has missed earnings expectations for three consecutive quarters. However, recent positive developments include the start of a Phase 3 trial for RASONQUE in pancreatic cancer and FDA Breakthrough Therapy Designation, fueling analyst optimism.

The outlook balances high-risk, high-reward potential. Strong analyst support (91.67% buy ratings) and a $253.35 consensus price target suggest significant upside, driven by the promising oncology pipeline. Key risks include substantial cash burn, lack of current revenue, and clinical trial execution uncertainties, making the stock suitable for investors comfortable with biotech volatility.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IONS
100% Buy0% Sell
Avg holding period · 0 Days
RVMD
51% Buy49% Sell
Avg holding period · 2 Days

About Ionis Pharmaceuticals Inc. Common Stock

Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.

Read more on IONS →

About Revolution Medicines Inc. Common Stock

Revolution Medicines develops precision medicines for cancer. Its programs focus on targeting RAS-driven cancers and related signaling pathways.

Read more on RVMD →