Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs O'Reilly Automotive Inc. Common Stock (ORLY) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Ionis Pharmaceuticals Inc. Common Stock vs O'Reilly Automotive Inc. Common Stock — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $42.5 (market cap $7.04B), while O'Reilly Automotive Inc. Common Stock trades at $87.2 (market cap $69.59B). The key difference: O'Reilly Automotive Inc. Common Stock is far larger — about 9.9× Ionis Pharmaceuticals Inc. Common Stock's market cap, and O'Reilly Automotive Inc. Common Stock is trading nearer its 52-week high, Ionis Pharmaceuticals Inc. Common Stock nearer its low. Which is the better fit depends on your goals.
| IONS | ORLY | |
|---|---|---|
Market Cap | $7.04B | $69.59B |
Volume | 2,977,440 | 3,367,517 |
Sector | Health | Consumer Cyclical |
52-Week High | $86.50 | $102.12 |
52-Week Low | $42.38 | $82.73 |
Typical Hold Time | 0 Days | — |
Enterprise Value | $6.60B | $78.92B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
No Aura AI signal available yet.
O'Reilly Automotive (ORLY) trades at $86.03, down 0.72% on the day, amid a mixed technical picture with a bullish overall signal but bearish moving averages. The company reported strong fundamentals with 2025 revenue of $17.78 billion and net income of $2.54 billion, maintaining a robust net income margin of 14.27%. Recent news highlights its defensive positioning in the auto parts market and upcoming Q3 2026 earnings release on October 28, 2026.
The outlook remains positive with a consensus price target of $106.09, implying significant upside. Key opportunities include resilient demand from an aging vehicle fleet and expansion plans in Mexico. Risks involve competitive pressures and potential macroeconomic headwinds affecting consumer spending on auto repairs. Analyst sentiment is strongly bullish with 59.57% buy ratings.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Investor sentiment on Pluang
What Pluang investors did over the last 30 days
Investor sentiment on Pluang
What Pluang investors did over the last 30 days
No sentiment data available yet.
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Ionis Pharmaceuticals Inc. Common Stock
Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.
Read more on IONS →About O'Reilly Automotive Inc. Common Stock
O'Reilly Automotive sells automotive aftermarket parts, tools, supplies, equipment, and accessories. It serves both professional service providers and do-it-yourself customers through its store network.
Read more on ORLY →
