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Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Orion Office REIT Inc (ONL) Price & Performance

Ionis Pharmaceuticals Inc. Common StockTrade
Orion Office REIT IncTrade

Price performance (Past 24H)

Key statistics

Ionis Pharmaceuticals Inc. Common Stock vs Orion Office REIT Inc — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.2 (market cap $7.10B), while Orion Office REIT Inc trades at $2.11 (market cap $119.79M). The key difference: Ionis Pharmaceuticals Inc. Common Stock is far larger — about 59.3× Orion Office REIT Inc's market cap, and Orion Office REIT Inc pays a 3.81% dividend while Ionis Pharmaceuticals Inc. Common Stock pays none. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Orion Office REIT Inc for 34 Days on average.

IONSONL
Market Cap
$7.10B$119.79M
Volume
2,027,457347,277
Sector
HealthReal Estate
52-Week High
$86.50$3.00
52-Week Low
$42.38$1.93
Typical Hold Time
0 Days34 Days
Enterprise Value
$6.66B$536.73M
Dividend Yield
—3.81%

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ionis Pharmaceuticals Inc. Common Stock

No Aura AI signal available yet.

Orion Office REIT Inc

ONL trades at $2.10, down 2.33% on the day, with a bearish technical signal despite oscillators showing some bullish momentum. The company reported Q2 2026 EPS of $0.42, beating expectations, but maintains negative net income margins and declining revenue trends from $208M in 2022 to $148M in 2025. Analyst consensus is split evenly between Buy and Hold ratings, with no Sell recommendations.

The outlook remains challenging with persistent net losses and high debt levels, though the deep discount to book value (P/B 0.19) offers potential upside if operational improvements materialize. Key risks include ongoing revenue contraction, negative profitability, and significant leverage exposure in the office REIT sector.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IONS
100% Buy0% Sell
Avg holding period · 0 Days
ONL

No sentiment data available yet.

About Ionis Pharmaceuticals Inc. Common Stock

Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.

Read more on IONS →

About Orion Office REIT Inc

Orion Office REIT Inc is a internally-managed REIT engaged in the ownership, acquisition, and management of a diversified portfolio of mission-critical and headquarters office buildings located in high quality suburban markets across the U.S. and leased primarily on a single-tenant net lease basis to creditworthy clients.

Read more on ONL →