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Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Moderna, Inc. (MRNA) Price & Performance

Ionis Pharmaceuticals Inc. Common StockTrade
Moderna, Inc.Trade

Price performance (Past 24H)

Key statistics

Ionis Pharmaceuticals Inc. Common Stock vs Moderna, Inc. — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.4 (market cap $7.10B), while Moderna, Inc. trades at $222 (market cap $90.35B). The key difference: Moderna, Inc. is far larger — about 12.7× Ionis Pharmaceuticals Inc. Common Stock's market cap, and Moderna, Inc. is trading nearer its 52-week high, Ionis Pharmaceuticals Inc. Common Stock nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Moderna, Inc. for 59 Days on average.

IONSMRNA
Market Cap
$7.10B$90.35B
Volume
2,027,45716,579,584
Sector
HealthHealth
52-Week High
$86.50$226.30
52-Week Low
$42.38$22.36
Typical Hold Time
0 Days59 Days
Enterprise Value
$6.66B$86.50B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ionis Pharmaceuticals Inc. Common Stock

No Aura AI signal available yet.

Moderna, Inc.

Moderna (MRNA) trades at $216.25, up 1.17% with a bullish technical signal and recent Nasdaq-100 inclusion driving momentum. Despite beating Q2 2026 EPS estimates, the company faces fundamental challenges with a net income margin of -142.58% and declining revenue from $18.9B in 2022 to $1.92B in 2025. The stock's 500% rally in 2026 has pushed valuations to elevated levels with a P/S of 38.5, creating divergence between technical strength and financial performance.

The outlook remains polarized with Nasdaq inclusion providing institutional support but valuation concerns capping upside. Investment opportunity lies in the cancer vaccine pipeline, while risks include sustained profitability challenges and competitive pressures. Analyst consensus at $115.70 suggests significant downside from current levels, with only 28% recommending buy ratings amid ongoing operational cash flow deficits.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IONS
100% Buy0% Sell
Avg holding period · 0 Days
MRNA
83% Buy17% Sell
Avg holding period · 59 Days

About Ionis Pharmaceuticals Inc. Common Stock

Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.

Read more on IONS →

About Moderna, Inc.

Moderna, Inc. operates as a clinical stage biotechnology company. The Company focuses on the discovery and development of messenger RNA (mRNA) therapeutics and vaccines. Moderna develops mRNA medicines for infectious, immuno-oncology, and cardiovascular diseases.

Read more on MRNA →