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Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Mesoblast Limited (MESO) Price & Performance

Ionis Pharmaceuticals Inc. Common StockTrade
Mesoblast LimitedTrade

Price performance (Past 24H)

Key statistics

Ionis Pharmaceuticals Inc. Common Stock vs Mesoblast Limited — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $42.5 (market cap $7.04B), while Mesoblast Limited trades at $13.76 (market cap $1.83B). The key difference: Ionis Pharmaceuticals Inc. Common Stock is far larger — about 3.8× Mesoblast Limited's market cap, and Mesoblast Limited is more actively traded (259,445 versus 2,977,440). Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Mesoblast Limited for 15 Days on average.

IONSMESO
Market Cap
$7.04B$1.83B
Volume
2,977,440259,445
Sector
HealthHealth
52-Week High
$86.50$20.96
52-Week Low
$42.38$13.19
Typical Hold Time
0 Days15 Days
Enterprise Value
$6.60B$1.91B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Ionis Pharmaceuticals Inc. Common Stock

No Aura AI signal available yet.

Mesoblast Limited

MESO trades at $13.895, down 2.63% with bearish technical signals. The company reported substantial revenue growth to $120M in 2026 but remains unprofitable with a net margin of -47.82%. Recent FDA approval for Ryoncil potency assay and completion of Phase 3 back pain trial represent significant milestones. The stock shows mixed sentiment with 45% analyst buy ratings against bearish technical indicators.

While MESO demonstrates strong revenue growth potential and pipeline progress, persistent losses and negative profitability metrics present substantial risk. The company's cash position of $161M provides runway, but investors face volatility from clinical trial outcomes and path to profitability challenges.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

IONS
100% Buy0% Sell
Avg holding period · 0 Days
MESO

No sentiment data available yet.

About Ionis Pharmaceuticals Inc. Common Stock

Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.

Read more on IONS →

About Mesoblast Limited

Mesoblast Limited is a global leader in allogeneic cellular medicines. The company develops innovative, commercially-ready mesenchymal lineage cell (MLC) technology for the treatment of various inflammatory and cardiovascular conditions. Their pipeline focuses on leveraging the anti-inflammatory, tissue repair, and immune-modulating properties of these cells for diseases with high unmet medical needs, such as acute graft versus host disease (aGVHD) and chronic heart failure.

Read more on MESO →