Ionis Pharmaceuticals Inc. Common Stock vs McKesson Corporation — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.32 (market cap $7.10B), while McKesson Corporation trades at $1,001.07 (market cap $113.86B). The key difference: McKesson Corporation is far larger — about 16× Ionis Pharmaceuticals Inc. Common Stock's market cap, and McKesson Corporation pays a 0.39% dividend while Ionis Pharmaceuticals Inc. Common Stock pays none. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and McKesson Corporation for 74 Days on average.
| IONS | MCK | |
|---|---|---|
Market Cap | $7.10B | $113.86B |
Volume | 2,027,457 | 767,917 |
Sector | Health | Health |
52-Week High | $86.50 | $995.69 |
52-Week Low | $42.38 | $725.17 |
Typical Hold Time | 0 Days | 74 Days |
Enterprise Value | $6.66B | $120.40B |
Dividend Yield | — | 0.39% |
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McKesson (MCK) trades at $961.88, up 0.64% today, near its 52-week high and above the consensus price target of $956.43. The stock shows strong technical momentum with bullish moving averages and recent earnings beats. Revenue grew to $359.05B in 2025, with net income of $3.30B, though margins remain thin. Positive sentiment is fueled by a key partnership extension with CVS Health through 2032 and reaffirmed guidance.
Outlook remains positive with analyst consensus strongly bullish (80.65% buy ratings), supported by oncology and specialty distribution growth. Risks include drug pricing pressure and policy uncertainty. The stock's current valuation at a P/E of 26.2 reflects growth expectations, but investors should monitor margin sustainability amid rising costs.
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Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.
Read more on IONS →McKesson is a leading wholesaler of branded, generic, and specialty pharmaceutical products to pharmacies (retail chains, independent, and mail order), hospitals networks, and healthcare providers. Along with AmerisourceBergen and Cardinal Health, the three account for well over 90% of the U.S. pharmaceutical wholesale industry. McKesson is currently divesting from its pharmaceutical wholesale and distribution in Europe and Canada in order to redeploy capital to strategic growth areas in the U.S. (oncology network and ecosystem, and biopharma services). Additionally, the company supplies medical-surgical products and equipment to healthcare facilities and provides a variety of technology solutions for pharmacies.
Read more on MCK →