Compare Ionis Pharmaceuticals Inc. Common Stock (IONS) vs Intuitive Surgical, Inc. (ISRG) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Ionis Pharmaceuticals Inc. Common Stock vs Intuitive Surgical, Inc. — how do they compare? Ionis Pharmaceuticals Inc. Common Stock trades at $43.2 (market cap $7.10B), while Intuitive Surgical, Inc. trades at $422.44 (market cap $148.46B). The key difference: Intuitive Surgical, Inc. is far larger — about 20.9× Ionis Pharmaceuticals Inc. Common Stock's market cap, and Intuitive Surgical, Inc. is trading nearer its 52-week high, Ionis Pharmaceuticals Inc. Common Stock nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Ionis Pharmaceuticals Inc. Common Stock for 0 Days and Intuitive Surgical, Inc. for 84 Days on average.
| IONS | ISRG | |
|---|---|---|
Market Cap | $7.10B | $148.46B |
Volume | 2,027,457 | 1,914,576 |
Sector | Health | Health |
52-Week High | $86.50 | $592.85 |
52-Week Low | $42.38 | $332.02 |
Typical Hold Time | 0 Days | 84 Days |
Enterprise Value | $6.66B | $143.25B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
No Aura AI signal available yet.
Intuitive Surgical (ISRG) trades at $422.06, down 1.3% on the day, but maintains strong fundamentals with consistent earnings beats and robust revenue growth from $6.2B in 2022 to $10.1B in 2025. The stock shows bullish technical signals with support at $414 and resistance at $431, while analyst consensus remains strongly positive with a $480.78 price target. Recent expansion into India and Japan helps offset China weakness, with da Vinci 5 upgrades driving recurring revenue streams.
ISRG presents a compelling growth opportunity with market leadership in robotic surgery and expanding international presence, though elevated valuation multiples (P/E 48.4) and competitive pressures warrant caution. The 70% buy rating from analysts suggests significant upside potential, but investors should monitor procedure growth rates and macroeconomic pressures affecting healthcare spending.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Investor sentiment on Pluang
What Pluang investors did over the last 30 days
Investor sentiment on Pluang
What Pluang investors did over the last 30 days
About Ionis Pharmaceuticals Inc. Common Stock
Ionis Pharmaceuticals Inc. is a biopharmaceutical company that develops RNA-targeted medicines using its antisense technology, with marketed treatments in neurology and cardiometabolic disease.
Read more on IONS →About Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and markets a robotic system for assisting minimally invasive surgery. It also provides the instrumentation, disposable accessories, and warranty services for the system. The company has placed nearly 7,000 da Vinci systems in hospitals worldwide, with more than 4,000 installations in the United States and a growing number in emerging markets.
Read more on ISRG →
