Incyte Corporation vs DENTSPLY SIRONA Inc — how do they compare? Incyte Corporation trades at $118 (market cap $23.11B), while DENTSPLY SIRONA Inc trades at $13.67 (market cap $2.70B). The key difference: Incyte Corporation is far larger — about 8.6× DENTSPLY SIRONA Inc's market cap, and DENTSPLY SIRONA Inc pays a 5.04% dividend while Incyte Corporation pays none. Which is the better fit depends on your goals.
| INCY | XRAY | |
|---|---|---|
Market Cap | $23.11B | $2.70B |
Sector | Health | Health |
52-Week High | $118.52 | $16.85 |
52-Week Low | $67.38 | $9.64 |
Enterprise Value | $19.13B | $4.84B |
Dividend Yield | — | 5.04% |
Signals from Pluang's Aura AI — not financial advice
INCY trades at $115.66, down 1.36% on the day, with a bullish technical signal from moving averages and strong fundamental performance including a 25.02% net income margin for 2025. Recent positive news includes regulatory approvals for Opzelura in Europe and the acquisition of Vega Therapeutics, expanding its hematology portfolio. Revenue grew to $5.14 billion in 2025, with earnings beating expectations in two of the last three quarters.
The outlook remains positive given robust profitability, pipeline advancements, and a majority analyst buy rating, though risks include competitive pressures and reliance on key drug performance. The stock's current price is slightly above the consensus target of $112.78, suggesting near-term consolidation potential amid longer-term growth catalysts.
DENTSPLY SIRONA (XRAY) trades at $13.57, down 3.48% with bearish technical indicators despite a bullish moving average signal. The company shows persistent challenges with negative net income margins (-17.06%) and declining revenue trends from $3.9B in 2022 to $3.7B in 2025. Recent Q1 2026 earnings missed estimates ($0.27 vs. $0.28 expected), continuing a pattern of underperformance. Analyst sentiment remains cautious with a 'Hold' consensus rating and $13.33 price target, slightly below current levels.
The stock faces significant fundamental headwinds including consecutive earnings misses, declining profitability, and rising debt-to-asset ratio (42.88% in 2025). While technical indicators show some bullish momentum, the weak financial performance and negative investor sentiment suggest limited near-term upside potential. The appointment of a new CFO and distribution expansions provide some operational optimism, but execution risks remain elevated.
Trailing returns across standard periods
Latest headlines on both assets
Incyte focuses on the discovery and development of small-molecule drugs. The firm's lead drug, Jakafi, treats two types of rare blood cancer and graft versus host disease and is partnered with Novartis. Incyte's other marketed drugs include rheumatoid arthritis treatment Olumiant (licensed to Lilly), and oncology drugs Iclusig (chronic myeloid leukemia), Pemazyre (cholangiocarcinoma), Tabrecta (lung cancer), and Monjuvi (diffuse large B-cell lymphoma). The firm's first dermatology product, Opzelura, was approved in 2021 for atopic dermatitis. Incyte's pipeline includes a broad array of oncology and dermatology programs.
Read more on INCY →Dentsply Sirona Inc is a global manufacturer and distributor of dental supplies and equipment. The company's operating segments include Technologies & Equipment, which is responsible for the design, manufacture, sales, and distribution of products including dental implants, CAD/CAM systems, orthodontic clear aligner products, imaging systems, treatment centers, instruments, as well as certain healthcare device products, primarily catheters
Read more on XRAY →