Illumina, Inc. vs Symbotic Inc — how do they compare? Illumina, Inc. trades at $193.06 (market cap $28.96B), while Symbotic Inc trades at $41.86 (market cap $5.21B). The key difference: Illumina, Inc. is far larger — about 5.6× Symbotic Inc's market cap, and Illumina, Inc. is trading nearer its 52-week high, Symbotic Inc nearer its low. Which is the better fit depends on your goals.
| ILMN | SYM | |
|---|---|---|
Market Cap | $28.96B | $5.21B |
Sector | Health | Technology |
52-Week High | $205.10 | $87.30 |
52-Week Low | $91.00 | $38.57 |
Enterprise Value | $30.32B | $3.46B |
Signals from Pluang's Aura AI — not financial advice
Illumina (ILMN) trades at $187.96, down 2.97% on the day, but maintains strong fundamental momentum with three consecutive quarterly earnings beats. The stock shows robust profitability with 66.38% gross margins and 18.34% net income margins, though technical indicators suggest near-term bearish pressure. Recent institutional buying activity and positive analyst coverage (51% buy ratings) support the stock's long-term growth narrative in the genomics sector.
The outlook remains positive with a consensus price target of $201.58 representing 7% upside potential. Key catalysts include continued NovaSeq X adoption and AI partnerships, while risks involve competitive pressures and execution challenges in achieving projected revenue growth. The company's turnaround from net losses to $850M profit in 2025 demonstrates improved operational efficiency.
SYM trades at $40.18, down 1.46% with bearish technical signals despite analyst optimism. Recent Q3 2026 earnings missed estimates at $0.09 vs. $0.13 expected, though revenue grew 21.7% year-over-year. The company shows weak profitability with a 0.31% net margin but maintains strong cash flow generation of $517 million in 2025. Technical indicators show bearish momentum with support at $39 and resistance at $42.
Outlook remains mixed with 61% analyst buy ratings and $60 consensus target suggesting 49% upside, but execution risks persist after recent earnings misses. Key catalysts include margin expansion and system deployments, while risks include competitive pressure and volatile earnings performance. The stock offers growth potential but requires careful monitoring of quarterly execution.
Trailing returns across standard periods
Latest headlines on both assets
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
Read more on ILMN →Symbotic is an automation technology leader that provides an end-to-end, A.I.-powered robotic platform for large-scale warehouse operations. By utilizing untethered, high-speed autonomous bots and sophisticated vision systems, Symbotic transforms traditional distribution centers into high-density strategic assets. The company serves the world’s largest retailers and wholesalers—most notably Walmart—while expanding into 'Warehouse-as-a-Service' through its GreenBox joint venture to democratize advanced automation for smaller enterprises.
Read more on SYM →