Illumina, Inc. vs Sirius XM Holdings Inc — how do they compare? Illumina, Inc. trades at $191.6 (market cap $27.94B), while Sirius XM Holdings Inc trades at $30.23 (market cap $10.30B). The key difference: Illumina, Inc. is far larger — about 2.7× Sirius XM Holdings Inc's market cap, and Sirius XM Holdings Inc pays a 3.53% dividend while Illumina, Inc. pays none. Which is the better fit depends on your goals.
| ILMN | SIRI | |
|---|---|---|
Market Cap | $27.94B | $10.30B |
Sector | Health | Media |
52-Week High | $194.33 | $31.22 |
52-Week Low | $91.00 | $19.92 |
Enterprise Value | $29.33B | $19.97B |
Dividend Yield | — | 3.53% |
Signals from Pluang's Aura AI — not financial advice
Illumina (ILMN) trades at $185.36, down 0.69% on the day, with a bullish technical signal from moving averages. The stock shows strong profitability with a 19.42% net income margin and has beaten EPS estimates for three consecutive quarters. Recent news highlights expansion of the Billion Cell Atlas program and upcoming Q2 2026 earnings on July 30.
Outlook remains positive with 51% analyst buy ratings, though the current price exceeds the $178 consensus target. Key risks include competitive pressure from Roche's new sequencer and China market weakness. Earnings growth and cost control initiatives support upside potential, but valuation multiples suggest limited near-term appreciation.
Sirius XM (SIRI) trades at $30.68, up 0.29% with a bullish technical signal and strong analyst support (58% buy ratings). The company shows improving fundamentals with three consecutive quarterly earnings beats and a return to profitability in 2025 after a 2024 loss. Recent developments include a strategic advertising partnership with YouTube and potential inclusion in the S&P MidCap 400 index.
The stock presents value characteristics with a P/E of 12.96 and P/B of 0.88, trading near the consensus price target of $31.17. Key risks include competitive pressures in media streaming and high debt levels despite recent improvement. Revenue stabilization and new partnerships provide catalysts, though execution risks remain in a challenging advertising environment.
Trailing returns across standard periods
Latest headlines on both assets
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
Read more on ILMN →SiriusXM Holdings is now composed of two businesses: SiriusXM and Pandora. SiriusXM transmits music, talk shows, sports, and news via its two satellite radio networks, primarily to consumers in vehicles who pay a subscription fee. The firm's radios come preinstalled on a wide range of light vehicles in the U.S. and Canada. The firm acquired Pandora Media in February 2019 via an all-stock transaction. Pandora is a streaming music platform that offers an ad-supported radio option and a paid on-demand service. Liberty Media owns 80% of SiriusXM, traded through its Liberty SiriusXM Group tracking stock.
Read more on SIRI →