Illumina, Inc. vs Rigetti Computing Inc — how do they compare? Illumina, Inc. trades at $180.13 (market cap $27.94B), while Rigetti Computing Inc trades at $14.73 (market cap $4.74B). The key difference: Illumina, Inc. is far larger — about 5.9× Rigetti Computing Inc's market cap, and Illumina, Inc. is trading nearer its 52-week high, Rigetti Computing Inc nearer its low. Which is the better fit depends on your goals.
| ILMN | RGTI | |
|---|---|---|
Market Cap | $27.94B | $4.74B |
Sector | Health | Technology |
52-Week High | $194.33 | $56.34 |
52-Week Low | $91.00 | $12.90 |
Enterprise Value | $29.33B | $4.33B |
Signals from Pluang's Aura AI — not financial advice
Illumina (ILMN) trades at $185.36, down 0.69% on the day, with a bullish technical signal from moving averages. The stock shows strong profitability with a 19.42% net income margin and has beaten EPS estimates for three consecutive quarters. Recent news highlights expansion of the Billion Cell Atlas program and upcoming Q2 2026 earnings on July 30.
Outlook remains positive with 51% analyst buy ratings, though the current price exceeds the $178 consensus target. Key risks include competitive pressure from Roche's new sequencer and China market weakness. Earnings growth and cost control initiatives support upside potential, but valuation multiples suggest limited near-term appreciation.
Rigetti Computing (RGTI) trades at $14.25, up 0.99% on the day, with a bearish technical signal despite bullish oscillators. The company shows significant financial challenges with a net income margin of -2,253.59% and negative cash flow from operations of $58.54M in 2025. Recent earnings have consistently beaten expectations, and analyst consensus remains strongly bullish with an average price target of $32.67, representing 129% upside potential from current levels.
While RGTI faces substantial execution risks in the pre-commercial quantum computing space, its government contracts and technological positioning offer long-term potential. Investors should weigh the company's speculative nature against analyst optimism and the emerging quantum computing market opportunity, with careful attention to cash burn and commercialization timelines.
Trailing returns across standard periods
Latest headlines on both assets
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
Read more on ILMN →Rigetti Computing, Inc. is a pioneer in quantum computing, focusing on developing and deploying quantum-classical computing systems. The company designs and fabricates superconducting quantum processors and integrates them with a full-stack software and control platform. Rigetti offers access to its quantum computers through the cloud, aiming to solve complex computational problems that are intractable for classical computers, with applications in finance, chemistry, and machine learning.
Read more on RGTI →