Illumina, Inc. vs Invesco NASDAQ 100 ETF — how do they compare? Illumina, Inc. trades at $192.38 (market cap $29.12B), while Invesco NASDAQ 100 ETF trades at $297.63. Which is the better fit depends on your goals.
| ILMN | QQQM | |
|---|---|---|
Market Cap | $29.12B | — |
Sector | Health | Broad Market / Factor |
52-Week High | $205.10 | $307.23 |
52-Week Low | $91.00 | $229.87 |
Enterprise Value | $30.48B | — |
Signals from Pluang's Aura AI — not financial advice
Illumina (ILMN) trades at $192.57, up 0.4% on the day, with a bearish technical signal but strong fundamental performance. The stock has consistently beaten earnings estimates in recent quarters, with Q2 2026 EPS of $1.31 exceeding expectations. Revenue remains stable around $4.3B, and profitability has improved significantly, with a net income margin of 19.57% in 2025. The company maintains robust cash flow from operations of $1.08B in 2025.
The outlook is mixed; strong fundamentals and analyst buy ratings support upside to the $201.58 consensus target, but technical weakness and high valuation ratios pose near-term risks. Key opportunities include sustained earnings beats and AI initiatives, while risks involve competitive pressures and execution challenges in a volatile market.
QQQM, tracking the Nasdaq-100, trades at $298.55, up 0.59% with a bullish technical signal from moving averages. The ETF benefits from lower fees compared to QQQ, attracting cost-conscious investors. Recent news highlights its inclusion in retirement portfolios and strong inflows into Nasdaq-focused ETFs, supported by tech sector performance.
Outlook remains positive due to tech-led growth, but risks include market volatility and concentration in mega-cap stocks. The ETF offers exposure to high-growth companies, with institutional activity showing mixed signals, such as Bank of America reducing its position in Q2 2026.
Trailing returns across standard periods
Latest headlines on both assets
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
Read more on ILMN →QQQM is an ETF designed to track the performance of the NASDAQ-100 Index. It provides exposure to the 100 largest non-financial companies listed on the NASDAQ. Positioned as a lower-cost and more long-term-investor-friendly alternative to its peer QQQ, QQQM offers the same fundamental market exposure but typically has a lower share price and is structured to appeal to investors focused on accumulation rather than active trading.
Read more on QQQM →