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Compare Illumina, Inc. (ILMN) vs O'Reilly Automotive Inc. Common Stock (ORLY) Price & Performance

Illumina, Inc.Trade
O'Reilly Automotive Inc. Common StockTrade

Price performance (Past 24H)

Key statistics

Illumina, Inc. vs O'Reilly Automotive Inc. Common Stock — how do they compare? Illumina, Inc. trades at $265 (market cap $40.43B), while O'Reilly Automotive Inc. Common Stock trades at $85.91 (market cap $68.45B). The key difference: O'Reilly Automotive Inc. Common Stock is the larger of the two by market cap, and Illumina, Inc. is trading nearer its 52-week high, O'Reilly Automotive Inc. Common Stock nearer its low. Which is the better fit depends on your goals.

ILMNORLY
Market Cap
$40.43B$68.45B
Volume
2,948,6266,667,530
Sector
HealthConsumer Cyclical
52-Week High
$293.69$103.05
52-Week Low
$91.00$82.73
Typical Hold Time
83 Days—
Enterprise Value
$41.79B$77.77B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Illumina, Inc.

Illumina (ILMN) trades at $264.40, down 3.34% on the day but up significantly year-to-date with strong technical momentum. The stock shows bullish moving average signals and trades near pivot point resistance at $268. Fundamentally, the company has delivered three consecutive quarterly earnings beats and returned to profitability in 2025 with $850 million net income after previous losses. Recent catalysts include S&P 500 inclusion effective September 21, 2026, and growing AI integration in genomics applications.

The outlook remains positive with analyst consensus favoring Buy ratings (54%) and a $241 price target, though current price exceeds consensus. Key opportunities include sequencing growth and AI-driven biological data expansion, while risks involve China market headwinds and elevated valuation multiples. Earnings growth and S&P 500 inclusion provide near-term catalysts, but the stock trades at premium valuations with P/E of 49.96 requiring sustained execution.

O'Reilly Automotive Inc. Common Stock

No Aura AI signal available yet.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

ILMN
96% Buy4% Sell
Avg holding period · 83 Days
ORLY

No sentiment data available yet.

Top news

Latest headlines on both assets

About Illumina, Inc.

Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.

Read more on ILMN →

About O'Reilly Automotive Inc. Common Stock

O'Reilly Automotive sells automotive aftermarket parts, tools, supplies, equipment, and accessories. It serves both professional service providers and do-it-yourself customers through its store network.

Read more on ORLY →