Illumina, Inc. vs Old Dominion Freight Line Inc — how do they compare? Illumina, Inc. trades at $189.49 (market cap $27.94B), while Old Dominion Freight Line Inc trades at $233.35 (market cap $48.20B). The key difference: Old Dominion Freight Line Inc is the larger of the two by market cap, and Old Dominion Freight Line Inc pays a 0.5% dividend while Illumina, Inc. pays none. Which is the better fit depends on your goals.
| ILMN | ODFL | |
|---|---|---|
Market Cap | $27.94B | $48.20B |
Sector | Health | Industrials |
52-Week High | $194.33 | $248.73 |
52-Week Low | $91.00 | $126.29 |
Enterprise Value | $29.33B | $47.95B |
Dividend Yield | — | 0.5% |
Signals from Pluang's Aura AI — not financial advice
Illumina (ILMN) trades at $185.36, down 0.69% on the day, with a bullish technical signal from moving averages. The stock shows strong profitability with a 19.42% net income margin and has beaten EPS estimates for three consecutive quarters. Recent news highlights expansion of the Billion Cell Atlas program and upcoming Q2 2026 earnings on July 30.
Outlook remains positive with 51% analyst buy ratings, though the current price exceeds the $178 consensus target. Key risks include competitive pressure from Roche's new sequencer and China market weakness. Earnings growth and cost control initiatives support upside potential, but valuation multiples suggest limited near-term appreciation.
Old Dominion Freight Line (ODFL) trades at $231.79, down 0.88% on the day, with a bullish technical signal supported by moving averages. The company maintains strong profitability with an 18.46% net income margin and has beaten earnings estimates for three consecutive quarters. Recent news highlights improved LTL metrics and a quarterly dividend of $0.29 per share, though valuation remains elevated with a P/E of 48.82.
ODFL's outlook is supported by operational excellence and a debt-light balance sheet, but high valuation and competitive pressures from players like Amazon pose risks. Analyst consensus is mixed with a $233.67 price target, suggesting limited upside from current levels amid economic uncertainties in the freight sector.
Trailing returns across standard periods
Latest headlines on both assets
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
Read more on ILMN →Old Dominion Freight Line is the fourth-largest less-than-truckload carrier in the United States, with more than 240 service centers and 9,200-plus tractors. OD is by far one of the most disciplined and efficient providers in the trucking industry, and its profitability and capital returns stand head and shoulders above its peers. Strategic initiatives revolve around increasing network density through market share gains and maintaining industry-leading service via consistent infrastructure investment.
Read more on ODFL →