Illumina, Inc. vs Realty Income Corp — how do they compare? Illumina, Inc. trades at $189.49 (market cap $27.94B), while Realty Income Corp trades at $64.96 (market cap $60.78B). The key difference: Realty Income Corp is far larger — about 2.2× Illumina, Inc.'s market cap, and Realty Income Corp pays a 4.99% dividend while Illumina, Inc. pays none. Which is the better fit depends on your goals.
| ILMN | O | |
|---|---|---|
Market Cap | $27.94B | $60.78B |
Sector | Health | Real Estate |
52-Week High | $194.33 | $67.56 |
52-Week Low | $91.00 | $55.93 |
Enterprise Value | $29.33B | $90.58B |
Dividend Yield | — | 4.99% |
Signals from Pluang's Aura AI — not financial advice
Illumina (ILMN) trades at $185.36, down 0.69% on the day, with a bullish technical signal from moving averages. The stock shows strong profitability with a 19.42% net income margin and has beaten EPS estimates for three consecutive quarters. Recent news highlights expansion of the Billion Cell Atlas program and upcoming Q2 2026 earnings on July 30.
Outlook remains positive with 51% analyst buy ratings, though the current price exceeds the $178 consensus target. Key risks include competitive pressure from Roche's new sequencer and China market weakness. Earnings growth and cost control initiatives support upside potential, but valuation multiples suggest limited near-term appreciation.
Realty Income (O) trades at $65.04, down 1.02% today, near the analyst consensus price target of $67.50. The stock shows a bullish technical setup with strong moving average signals, though RSI levels suggest mild overbought conditions. Recent earnings have missed expectations for three consecutive quarters, but revenue growth remains steady, rising to $5.75B in 2025. The company maintains a high dividend yield with consistent payouts, supported by robust operating cash flow of $4.0B.
Outlook is cautiously optimistic with a solid dividend profile and expansion through partnerships, but elevated P/E of 53.86 and recent earnings misses pose valuation and execution risks. Debt levels have increased, with debt-to-asset ratio reaching 39.93% in 2025, adding financial leverage concerns. Analyst sentiment is mixed with 41% buy ratings, reflecting balanced views on growth potential versus rich valuations.
Trailing returns across standard periods
Latest headlines on both assets
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
Read more on ILMN →Realty Income owns roughly 11,400 properties, most of which are freestanding, single-tenant, triple-net-leased retail properties. Its properties are located in 49 states and Puerto Rico and are leased to 250 tenants from 47 industries. Recent acquisitions have added industrial, office, manufacturing, and distribution properties, which make up roughly 17% of revenue.
Read more on O →